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    Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial

    234582_234582.pdf (1.311Mb)
    Access Status
    Open access
    Authors
    Titov, N.
    Dear, B.
    Staples, L.
    Terides, M.
    Karin, E.
    Sheehan, J.
    Johnston, L.
    Gandy, M.
    Fogliati, V.
    Wootton, B.
    McEvoy, Peter
    Date
    2015
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Titov, N. and Dear, B. and Staples, L. and Terides, M. and Karin, E. and Sheehan, J. and Johnston, L. et al. 2015. Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial. Journal of Anxiety Disorders. 35: pp. 88-102.
    Source Title
    Journal of Anxiety Disorders
    DOI
    10.1016/j.janxdis.2015.08.002
    ISSN
    0887-6185
    School
    School of Psychology and Speech Pathology
    Remarks

    This open access article is distributed under the Creative Commons license http://creativecommons.org/licenses/by-nc-nd/4.0/

    URI
    http://hdl.handle.net/20.500.11937/27198
    Collection
    • Curtin Research Publications
    Abstract

    Disorder-specific cognitive behavior therapy (DS-CBT) is effective at treating major depressive disorder (MDD) while transdiagnostic CBT (TD-CBT) addresses both principal and comorbid disorders by targeting underlying and common symptoms. The relative benefits of these two models of therapy have not been determined. Participants with MDD (n = 290) were randomly allocated to receive an internet delivered TD-CBT or DS-CBT intervention delivered in either clinician-guided (CG-CBT) or self-guided (SG-CBT) formats. Large reductions in symptoms of MDD (Cohen’s d ≥ 1.44; avg. reduction ≥ 45%) and moderate-to-large reductions in symptoms of comorbid generalised anxiety disorder (Cohen’s d ≥ 1.08; avg. reduction ≥ 43%), social anxiety disorder (Cohen’s d ≥ 0.65; avg. reduction ≥ 29%) and panic disorder (Cohen’s d ≥ 0.45; avg. reduction ≥ 31%) were found. No marked or consistent differences were observed across the four conditions, highlighting the efficacy of different forms of CBT at treating MDD and comorbid disorders.

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