Diagnostic procedures in autism spectrum disorders: a systematic literature review
MetadataShow full item record
At present, ‘gold standard’ diagnosis of autism spectrum disorders (ASD) is a lengthy and time consuming process that requires suitably qualified multi-disciplinary team (MDT) personnel to assess behavioural, historical, and parent-report information to determine a diagnosis. A number of different tools have been developed to assist in determination. To optimise the diagnostic procedures, the best diagnostic instruments need to be identified. This study is a systematic review addressing the accuracy, reliability, validity and utility of reported diagnostic tools and assessments. To be included in this review, studies must have (1) identified an ASD diagnostic tool; (2) investigated either diagnostic procedure or the tools or personnel required; (3) be presented in English; (4) be conducted in the Western world; (5) be one of three types of studies [adapted from Samtani et al. in Cochrane Database Syst Rev 3:1–13, 2011], viz. (a) cohort studies or cross-sectional studies, (b) randomised studies of test accuracy, (c) case–control studies. MEDLINE, PsychINFO, Scopus, EMBASE, and Cochrane Library databases were scrutinised for relevant literature published from 2000 inclusive on 20th January 2012. In total, 68 articles were included. 17 tools were assessed. However, many lacked an evidence base of high quality-independent studies. The Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule (ADOS) stood out with the largest evidence base and highest sensitivity and specificity. When the ADI-R and ADOS were used in combination they revealed levels of accuracy very similar to the correct classification rates for the current ‘gold standard’ diagnostic procedure viz. 80.8 % for ASD. There is scope for future studies on the use of the ADI-R and ADOS in combination.
Showing items related by title, author, creator and subject.
Zander, E.; Willfors, C.; Berggren, S.; Coco, C.; Holm, A.; Jifält, I.; Kosieradzki, R.; Linder, J.; Nordin, V.; Olafsdottir, K.; Bölte, Sven (2017)Background: The Autism Diagnostic Interview-Revised (ADI-R) is considered a first choice assessment tool in autism spectrum disorder. Nevertheless, despite its wide use in psychiatric practice and recommendations by various ...
Diagnosing autism in a clinical sample of adults with intellectual disabilities: How useful are the ADOS and the ADI-R?Sappok, T.; Diefenbacher, A.; Budczies, J.; Schade, C.; Grubich, C.; Bergmann, T.; Bölte, Sven; Dziobek, I. (2013)Intellectual disability (ID) and autism spectrum disorder (ASD) are frequently co-occurring conditions. Carefully diagnosing ASD in individuals with ID would allow for more tailored clinical interventions that would improve ...
An international qualitative study of functioning in autism spectrum disorder using the World Health Organization international classification of functioning, disability and health frameworkMahdi, S.; Viljoen, M.; Yee, T.; Selb, M.; Singhal, N.; Almodayfer, O.; Granlund, M.; de Vries, P.; Zwaigenbaum, L.; Bolte, Sven (2018)Â© 2017 The Authors Autism Research published by International Society for Autism Re search and Wiley Periodicals, Inc. This is the third in a series of four empirical studies designed to develop International Classification ...