Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    The search for biomarkers of immune restoration disease associated with Mycobacterium tuberculosis in HIV patients beginning antiretroviral therapy

    Access Status
    Fulltext not available
    Authors
    Oliver, B.
    Price, Patricia
    Date
    2011
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Oliver, B. and Price, P. 2011. The search for biomarkers of immune restoration disease associated with Mycobacterium tuberculosis in HIV patients beginning antiretroviral therapy. Biomarkers in Medicine. 5 (2): pp. 149-154.
    Source Title
    Biomarkers in Medicine
    DOI
    10.2217/bmm.11.16
    ISSN
    1752-0363
    School
    School of Biomedical Sciences
    URI
    http://hdl.handle.net/20.500.11937/28736
    Collection
    • Curtin Research Publications
    Abstract

    Immune restoration disease associated with Mycobacterium tuberculosis is a complication of antiretroviral therapy seen in a subset of HIV-1 patients soon after they commence antiretroviral therapy. It is characterized by a 'paradoxical' worsening of treated tuberculosis or an 'unmasking' of subclinical tuberculosis. As antiretroviral therapy becomes increasingly available in countries with a high prevalence of tuberculosis, this form of immune restoration disease will become more common. Here we summarize biomarkers that may illuminate immunopathogenesis and assist in diagnosis. © 2011 Future Medicine Ltd.

    Related items

    Showing items related by title, author, creator and subject.

    • Mycobacterial antibody levels and immune restoration disease in HIV patients treated in South East Asia
      Sumatoh, H.; Oliver, B.; Kumar, M.; Elliott, J.; Vonthanak, S.; Vun, M.; Singh, S.; Agarwal, U.; Kumar, A.; Tan, H.; Kamarulzaman, A.; Yunihastuti, E.; Saraswati, H.; Price, Patricia (2011)
      Aim: Immune restoration disease (IRD) associated with Mycobacterium tuberculosis parallels the reconstitution of a pathogen-specific Th1 response. However, it is not clear whether humoral responses to M. tuberculosis ...
    • Predictors of mortality in a cohort of tuberculosis/HIV co-infected patients in Southwest Ethiopia
      Gesesew, H.; Tsehayneh, B.; Massa, D.; Gebremedhin, Amanuel Tesfay; Kahsay, H.; Mwanri, L. (2016)
      Background: Tuberculosis/HIV co-infection is a bidirectional and synergistic combination of two very important pathogens in public health. To date, there have been limited clinical data regarding mortality rates among ...
    • Tuberculosis associated immune reconstitution inflammatory syndrome in patients infected with HIV: meningitis a potentially life threatening manifestation
      Agarwal, U.; Kumar, A.; Behera, D.; French, M.; Price, Patricia (2012)
      Background: Tuberculosis (TB) is the most common co infection in HIV-infected persons in India, requiring concomitant administration of anti TB and antiretroviral therapies. Paradoxical worsening of tuberculosis after ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.