Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Precerebellar cell groups in the hindbrain of the mouse defined by retrograde tracing and correlated with Wnt1-cre genetic labeling

    189141_183324 Table.pdf (142.7Kb)
    183324_183324.pdf (507.5Kb)
    Access Status
    Open access
    Authors
    Fu, Y.
    Tvrdik, P.
    Makki, N.
    Paxinos, G.
    Watson, Charles
    Date
    2011
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Fu, YuHong and Tvrdik, Petr and Makki, Nadja and Paxinos, George and Watson, Charles. 2011. Precerebellar cell groups in the hindbrain of the mouse defined by retrograde tracing and correlated with Wnt1-Cre genetic labeling. The Cerebellum. 10 (3): pp. 570-584.
    Source Title
    The Cerebellum
    DOI
    10.1007/s12311-011-0266-1
    ISSN
    14734222
    School
    Australian Biosecurity CRC- Emerging Infectious Diseases (CRC-Core)
    Remarks

    NOTICE: This is the author’s version of a work in which changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication.

    The final publication is available at: http://www.springerlink.com

    URI
    http://hdl.handle.net/20.500.11937/2877
    Collection
    • Curtin Research Publications
    Abstract

    The precerebellar nuclei are hindbrain and spinal cord centers that send fibers to the cerebellum. The neurons of the major hindbrain precerebellar nuclei are derived from the rhombic lip. Wnt1, a developmentally important gene involved in intercellular signaling, is expressed in the developing rhombic lip. We sought to investigate the relationship between the cell clusters expressing Wnt1 and the precerebellar nuclei in the hindbrain. We therefore defined the hindbrain precerebellar nuclei by retrograde tracing, following cerebellar injections of HRP, and compared these results with the cell clusters expressing Wnt1 in newborn mice. We found that 39 distinct hindbrain nuclei project to the cerebellum. Of these nuclei, all but three (namely the oral pontine reticular nucleus, the caudal pontine reticular nucleus, and the subcoeruleus nucleus) contain neurons expressing Wnt1. This shows a high degree of overlap between the precerebellar nuclei and the nuclei that express Wnt1. However, it should be noted that neurons expressing Wnt1 are also found in the superior olivary complex, which is a basal plate derivative lacking cerebellar projections.

    Related items

    Showing items related by title, author, creator and subject.

    • The spinal precerebellar nuclei: Calcium binding proteins and gene expression profile in the mouse
      Fu, Y.; Sengul, G.; Paxinos, G.; Watson, Charles (2012)
      We have localized the spinocerebellar neuron groups in C57BL/6J mice by injecting the retrograde neuronal tracer Fluoro-Gold into the cerebellum and examined the distribution of SMI 32 and the calcium-binding proteins ...
    • The arcuate nucleus of the C57BL/6J mouse hindbrain is a displaced part of the inferior olive
      Fu, Y.; Watson, Charles (2012)
      The arcuate nucleus is a prominent cell group in the human hindbrain, characterized by its position on the pial surface of the pyramid. It is considered to be a precerebellar nucleus and has been implicated in the pathology ...
    • The interfascicular trigeminal nucleus: A precerebellar nucleus in the mouse defined by retrograde neuronal tracing and genetic fate mapping
      Fu, Y.; Tvrdik, P.; Makki, N.; Machold, R.; Paxinos, G.; Watson, Charles (2012)
      We have found a previously unreported precerebellar nucleus located among the emerging fibers of the motor root of the trigeminal nerve in the mouse, which we have called the interfascicular trigeminal nucleus (IF5). This ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.