View Item 

Haemodynamic Effect of Coronary Angulations on Subsequent Development of Coronary Artery Disease: A Preliminary Study

Access Status
Open access
Authors
Chachaina, T.
Sun, Zhonghua
Jewkes, James
Date
2010
Type
Conference Paper

Metadata
Show full item record
Citation
Chachaina, T. and Sun, Zhonghua and Jewkes, J. 2010. Haemodynamic Effect of Coronary Angulations on Subsequent Development of Coronary Artery Disease: A Preliminary Study, in Lewis, A. (ed), Sixth IEEE International Conference on e-Science workshops, Dec 7 2010, pp. 39-43. Brisbane, QLD: IEEE.
Source Title
IEEE Computer Society
Source Conference
Sixth IEEE International Conference on e-Science workshops
DOI
School
Department of Imaging and Applied Physics
Remarks

Copyright © 2010 IEEE This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.

URI
Collection
Abstract

The aim of this study is to investigate the hemodynamic effect of the angulations in the left coronary bifurcation on subsequent development of coronary artery disease. Eight 3D left coronary artery models were generated based on the anatomical details and simulated for numerical analysis. The angulations at the left coronary bifurcation were simulated with angles ranging from 120°, 105°, 90°, 75°, 60°, 45°, 30° to 15°. Computational fluid dynamic models were produced for analysis of flow velocity, wall pressure and wall shear stress. Our results showed that wide angled models produced low wall shear stress and high wall pressure at the left coronary bifurcation regions, whereas, flow pattern was more smooth and laminar with narrow angled models than those with wide angle models. Our analysis indicates the flow-field correlation between coronary angulation and development of atherosclerosis. Future studies are required to analyse the realistic coronary models from patients' data with different degree of coronary stenosis.