Topical Microneedle Drug Delivery Enhanced with Magnetophoresis
MetadataShow full item record
Proteins and peptides are coming of age as targeted biological therapies. A broad range of peptides have now been approved by the FDA and other regulatory agencies for use as therapeutics. Likewise, large proteins such as infliximab and botox are commonly used to treat skin conditions. The most widely used delivery approach for peptides and proteins is parenteral injection, largely due to oral instability and the lack of a suitable alternative. Intense research is being done to improve the short half-lives of these biological therapies and find suitable alternative delivery routes. Transdermal delivery holds promise as an improved delivery route because the skin has low levels of enzymatic activity and can help drugs avoid first-pass metabolism. Further, topical delivery has the potential for direct treatment of skin disease for both therapeutic and cosmetic applications.
Showing items related by title, author, creator and subject.
Changes in caesarean delivery rates in Western Australia from 1995 to 2010 by gestational age at birthEinarsdöttir, K.; Ball, Stephen; Pereira, Gavin; Griffin, C.; Jacoby, P.; De Klerk, N.; Leonard, H.; Stanley, F. (2015)© 2015 John Wiley & Sons Ltd. Background The caesarean delivery rate in the developed world has been increasing. It is not well understood how caesarean delivery rates have changed by gestational age at birth in Western ...
Tan, K.; Danquah, M.; Sidhu, Amandeep; Yon, L.; Ongkudon, C. (2016)© 2016 Bentham Science Publishers.The search for smart delivery systems for enhanced pre-clinical and clinical pharmaceutical delivery and cell targeting continues to be a major biomedical research endeavor owing to ...
Prevalence and factors associated with non-utilization of healthcare facility for childbirth in rural and urban Nigeria: Analysis of a national population-based surveyAdewuyi, E.; Zhao, Yun; Auta, A.; Lamichhane, R. (2017)© Author(s) 2017. Aim: The aim of this study was to assess the rural-urban differences in the prevalence and factors associated with non-utilization of healthcare facility for childbirth (home delivery) in Nigeria. Methods: ...