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    Is body size associated with ovarian cancer in southern Chinese women?

    Access Status
    Fulltext not available
    Authors
    Dada, Su
    Pasalich, Maria
    Binns, Colin
    Lee, Andy
    Date
    2012
    Type
    Journal Article
    
    Metadata
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    Citation
    Dada, Su and Pasalich, Maria and Binns, Colin W. and Lee, Andy H. 2012. Is body size associated with ovarian cancer in southern Chinese women? Cancer Causes and Control. 23 (12): pp. 1977-1984.
    Source Title
    Cancer Causes and Control
    DOI
    10.1007/s10552-012-0075-y
    ISSN
    09575243
    URI
    http://hdl.handle.net/20.500.11937/29386
    Collection
    • Curtin Research Publications
    Abstract

    Purpose: To investigate the association between risk of ovarian cancer and body size among southern Chinese women. Methods: A hospital-based case–control study was undertaken in Guangzhou, Guangdong Province, from 2006 to 2008. Participants were 500 incident ovarian cancer patients and 500 controls, with a mean age of 59 years. Information on adult height and weight was obtained via face-to-face interview using a structured questionnaire. Logistic regression analyses were performed to assess the association between anthropometric factors and the ovarian cancer risk. Results: Compared with women having body weight ≤50 kg and body mass index (BMI) <18.5 kg/m2, the adjusted odds ratios (ORs) of ovarian cancer were 1.84 (95 % confidence interval (CI) 1.34–2.54) and 1.77 (95 % CI 1.04–3.02) in those women who had body weight >55 kg and BMI ≥23 kg/m2, respectively. Significant dose–response relationships were also observed for both weight and BMI (p<0.01). Body height was not significantly associated with ovarian cancer risk. Conclusion: Body weight and BMI were associated with increased risk of ovarian cancer in southern Chinese women.

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