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    Physical inactivity is associated with moderate-severe obstructive sleep apnea

    Access Status
    Fulltext not available
    Authors
    Simpson, L.
    McArdle, N.
    Eastwood, Peter
    Ward, K.
    Cooper, M.
    Wilson, A.
    Hillman, D.
    Palmer, L.
    Mukherjee, S.
    Date
    2015
    Type
    Journal Article
    
    Metadata
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    Citation
    Simpson, L. and McArdle, N. and Eastwood, P. and Ward, K. and Cooper, M. and Wilson, A. and Hillman, D. et al. 2015. Physical inactivity is associated with moderate-severe obstructive sleep apnea. Journal of Clinical Sleep Medicine. 11 (10): pp. 1091-1099A.
    Source Title
    Journal of Clinical Sleep Medicine
    DOI
    10.5664/jcsm.5078
    ISSN
    1550-9389
    School
    School of Physiotherapy and Exercise Science
    URI
    http://hdl.handle.net/20.500.11937/30046
    Collection
    • Curtin Research Publications
    Abstract

    Study Objectives: To investigate whether low levels of physical activity were associated with an increased occurrence of obstructive sleep apnea (OSA), OSA-related symptoms, and cardiometabolic risk. Methods: A case-control study design was used. OSA cases were patients referred to a sleep clinic for suspected OSA (n = 2,340). Controls comprised participants from the Busselton community (n = 1,931). Exercise and occupational activity were derived from questionnaire data. Associations were modelled using logistic and linear regression and adjusted for confounders. Results: In comparison with moderate exercise, the high, low, and nil exercise groups had an odds ratio (OR) for moderate-severe OSA of 0.6 (95% CI 0.5-0.8), 1.6 (95% CI 1.2-2.0), and 2.7 (95% CI 1.9-3.7), respectively. Relative to men in heavy activity occupations, men in medium, light and sedentary occupations had an OR for moderate-severe OSA of 1.7 (95% CI 1.1-2.5), 2.1 (95% CI 1.4-3.2), and 1.8 (95% CI 1.2-2.8), respectively. Relative to women in medium activity occupations, women in light and sedentary occupations had an OR for moderate-severe OSA of 4.2 (95% CI 2.6-7.2) and 3.5 (2.0-6.0). OSA patients who adequately exercised had lower: levels of doctor-diagnosed depression (p = 0.047); symptoms of fatigue (p < 0.0001); systolic (p = 0.015) and diastolic blood pressure (p = 0.015); and C-reactive protein (CRP) (p = 0.003). Conclusions: Low levels of physical activity were associated with moderate-severe OSA. Exercise in individuals with OSA is associated with lower levels of depression, fatigue, blood pressure and CRP.

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