Identification of a Potential Marker for Absence of Dark Fibre in Vicugna pacos (alpaca)
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The Melanocortin-1 receptor gene was sequenced in a group of 41 Australian alpacas and seven single nucleotide polymorphisms (SNPs) were identified within the coding region (D42D, N118N, L206L, E311E, T28A, G126S and R301C). Three of these SNP (T28A, G126S and R301C) showed an association with phenotypic colour variants when both skin and fibre colour were used to segregate animals into groups. We propose the identification of a haplotype (T28A/G126S), which appears to be a marker for the absence of dark pigment in alpaca fleeces. Animals with the G82/C126 combination did not have any dark pigment. Both A82G & C901T are potentially capable of altering MC1R function. It?s therefore possible that we have identified wild type (dominant) and loss-of-function (recessive) alleles of the alpaca MC1R gene.
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Novel mutations in Vicugna pacos (alpaca) Tyrp1 are not correlated with brown fibre colour phenotypesFeeley, Natasha; Bottomley, Steven; Munyard, Kylie (2016)© 2016 Elsevier B.V. The tyrosinase related protein 1 (Tyrp1) gene is a logical candidate to house the causative mutation for the brown fibre colour phenotype that exists in alpacas. Polymorphisms in Tyrp1 have been ...
Munyard, Kylie; Greeff, J. (2013)Some alpacas maintain fine fibre throughout life, while others suffer from significant coarsening of fibre as they age, a trait known as micron blowout. Micron blowout results in reduced productivity, through reduced yield ...
Munyard, Kylie (2013)This RIRDC report describes the research conducted as part of the alpaca colour genetics project to identify the genes involved in the inheritance of white colour in alpacas. Three approaches were used (Mendelian, physical ...