Show simple item record

dc.contributor.authorRobinson, J.
dc.contributor.authorPozzi-Langhi, S.
dc.contributor.authorPhillips, M.
dc.contributor.authorPearson, J.
dc.contributor.authorChristiansen, K.
dc.contributor.authorCoombs, Geoffrey
dc.contributor.authorMurray, R.
dc.identifier.citationRobinson, J.O. and Pozzi-Langhi, S and Phillips, M. and Pearson, J.C. and Christiansen, K.J. and Coombs, G.W. and Murray, R.J. 2012. Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia. European Journal of Clinical Microbiology and Infectious Diseases. 31 (9): pp. 2421-2428.

To determine the impact of infectious diseases consultation (IDC) in Staphylococcus aureus bacteraemia. All MRSA bacteraemia and a random subset of MSSA bacteraemia were retrospectively analysed. Out of 599 SAB episodes, 162 (27%) were followed by an IDC. Patients with IDC were younger and more frequently intravenous drug users, but fewer resided in a long-term care facility or were indigenous. Hospital length of stay was longer (29.5 vs 17 days, p < 0.001), and endocarditis (19.1% vs 7.3%, p < 0.001) and metastatic seeding (22.2% vs 10.1%, p < 0.001) were more frequent in the IDC group; however, SAPS II scores were lower in the IDC group (27 vs 37, p < 0.001). ICU admission rates in the two groups were similar. The isolate tested susceptible to empirical therapy more frequently in the IDC group (88.9% vs 78.0%, p = 0.003). Seven-day (3.1 vs 16.5%), 30-day (8.0% vs 27.0%) and 1-year mortality (22.2% vs 44.9%) were all lower in the IDC group (all p < 0.001). Multivariate analysis showed that effective initial therapy was the only variable associated with the protective effect of IDC. In patients with SAB, all-cause mortality was significantly lower in patients who had an IDC, because of the higher proportion of patients receiving effective initial antibiotics.

dc.titleFormal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia
dc.typeJournal Article
dcterms.source.titleEuropean Journal of Clinical Microbiology and Infectious Diseases
curtin.accessStatusFulltext not available

Files in this item


This item appears in the following Collection(s)

Show simple item record