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Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men

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Open access
Authors
Howie, Erin
Sui, X.
Lee, D.
Hooker, S.
Hebert, J.
Blair, S.
Date
2011
Type
Journal Article

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Howie, E. and Sui, X. and Lee, D. and Hooker, S. and Hebert, J. and Blair, S. 2011. Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men. Journal of Ageing Research. 2011. Article ID 805062 (10 p.).
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Journal of Ageing Research
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This article is published under the Open Access publishing model and distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ Please refer to the licence to obtain terms for any further reuse or distribution of this work.

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Abstract

This study examined the association between consumption of alcoholic beverages and all-cause and cardiovascular disease (CVD) mortality in a cohort of men (n = 31,367). In the Cox proportional hazards model adjusted for age, year of examination, body mass index (BMI), smoking, family history of CVD, and aerobic fitness, there were no significant differences in risk of all-cause mortality across alcohol intake groups. Risk of CVD mortality was reduced 29% in quartile 1 (HR = 0.71, 95% confidence interval(CI): 0.53, 0.95) and 25% in quartile 2 (HR = 0.75, 95% CI: 0.58, 0.98). The amount of alcohol consumed to achieve this risk reduction was <6 drinks/week; less than the amount currently recommended. The addition of other potential confounders and effect modifiers including blood pressure, insulin sensitivity, lipid levels, and psychological variables did not affect the magnitudeof association. Future research is needed to validate the current public health recommendations for alcohol consumption.