Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Trabecular bone texture detected by plain radiography is associated with an increased risk of knee replacement in patients with osteoarthritis: a six year prospective follow up study

    Access Status
    Open access via publisher
    Authors
    Podsiadlo, Pawel
    Ciccuttini, F
    Wolski, Marcin
    Stachowiak, Gwidon
    Wluka, A
    Date
    2013
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Podsiadlo, P and Ciccuttini, F and Wolski, M and Stachowiak, Gwidon and Wluka, A. 2013. Trabecular bone texture detected by plain radiography is associated with an increased risk of knee replacement in patients with osteoarthritis: a six year prospective follow up study. Abstracts / Osteoarthritis and Cartilage. 21 (Suppl.): pp. S137-S138.
    Source Title
    Osteoarthritis and Cartilage
    DOI
    10.1016/j.joca.2013.02.292
    ISSN
    1063-4584
    URI
    http://hdl.handle.net/20.500.11937/32320
    Collection
    • Curtin Research Publications
    Abstract

    Objective: To examine the association between trabecular bone texture and knee joint replacement (KJR) measured using a variance orientation transform (VOT) method. Methods: The association of trabecular bone texture and KJR was examined prospectively over 6 years in 123 subjects with symptomatic knee osteoarthritis (OA): data regarding KJR was available for 114 (93%). At baseline, weight-bearing anteroposterior tibio-femoral radiographs were acquired. Trabecular bone texture regions were selected from the medial and lateral subchondral tibia. The VOT method was applied to each region and five fractal bone texture parameters, i.e., mean fractal dimension (FDMEAN), fractal dimensions in the horizontal (FDH) and vertical (FDV) directions, and along the roughest part of trabecular bone (FDSta), and texture aspect ratio (Str) were calculated. The association between groups with increasing baseline fractal parameters (defined using tertiles) with risk of JR was examined using logistic regression. Results: 28 (25%) participants' study knees underwent KJR over 6 years. Participants with KJR had lower medial FDMEAN and FDH parameters (P=0.02 for difference). With increasing FDMEAN, adjusted for age, gender, body mass index (BMI), osteophyte grade, joint space narrowing (JSN) grade and WOMAC pain score, the odds of KJR was reduced (P=0.04 for trend). Conclusion: This study suggests that the texture of medial tibial trabecular bone measured from plain radiographs is related to the risk of KJR: with increasing FDMEAN (the overall measure of bone texture roughness) the risk of KJR was reduced, independent of other clinical predictors of joint replacement. Tibial trabecular bone texture may be a useful marker of disease progression and a target of therapy in OA.

    Related items

    Showing items related by title, author, creator and subject.

    • Baseline trabecular bone and its relation to incident radiographic knee osteoarthritis and increase in joint space narrowing score: directional fractal signature analysis in the MOST study
      Podsiadlo, P.; Nevitt, M.; Wolski, Marcin; Stachowiak, G.; Lynch, J.; Tolstykh, I.; Felson, D.; Segal, N.; Lewis, C.; Englund, M. (2016)
      Purpose: To explore the association of baseline trabecular bone structure with incident tibiofemoral (TF) osteoarthritis (OA) and with increase in joint space narrowing (JSN) score. Methods: The Multicenter Osteoarthritis ...
    • Early tibial subchondral bone texture changes after arthroscopic partial meniscectomy in knees without radiographic OA: A prospective cohort study
      Wolski, Marcin ; Thorlund, J.B.; Stachowiak, Gwidon ; Holsgaard-Larsen, A.; Creaby, M.W.; Jørgensen, G.M.; Englund, M.; Podsiadlo, Pawel (2020)
      Arthroscopic partial meniscectomy (APM) may lead to changes in underlying trabecular bone (TB) structure potentially promoting the development of knee joint osteoarthritis. Our aim was to investigate if there are early ...
    • Differences in trabecular bone texture between knees with and without radiographic osteoarthritis detected by fractal methods
      Podsiadlo, Pawel; Dahl, L; Englund, M; Lohmander, L; Stachowiak, Gwidon (2008)
      Objective: To develop an accurate method for quantifying differences in the trabecular structure in the tibial bone between subjects with and without knee osteoarthritis (OA). Methods: Standard knee radiographs were taken ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.