A novel multicomponent microwave-assisted synthesis of 5-aza-adenines
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Dolzhenko, Anton
Kalinina, S.
Kalinin, D.
Date
2013Type
Journal Article
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Dolzhenko, Anton V. and Kalinina, Svetlana A. and Kalinin, Dmitrii V. 2013. A novel multicomponent microwave-assisted synthesis of 5-aza-adenines. RSC Advances. 10 (3): pp. 15850-15855.
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RSC Advances
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Abstract
A novel multicomponent strategy for the efficient synthesis of 5-aza-adenines was developed. 5-Azaadenines were prepared in a one-pot fashion from 5-amino-1,2,4-triazoles, cyanamide and triethylorthoformate under microwave irradiation. The operational simplicity, efficiency and accessibility of thismethod make it highly attractive for the generation of bioactive compound libraries