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    Twisted Aspirin Crystals

    Access Status
    Fulltext not available
    Authors
    Cui, X.
    Rohl, Andrew
    Shtukenberg, A.
    Kahr, B.
    Date
    2013
    Type
    Journal Article
    
    Metadata
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    Citation
    Cui, Xiaoyan and Rohl, Andrew L. and Shtukenberg, Alexander and Kahr, Bart. 2013. Twisted Aspirin Crystals. Journal of the American Chemical Society. 135 (9): pp. 3395-3398.
    Source Title
    Journal of the American Chemical Society
    DOI
    10.1021/ja400833r
    ISSN
    0001-4842
    URI
    http://hdl.handle.net/20.500.11937/35478
    Collection
    • Curtin Research Publications
    Abstract

    Banded spherulites of aspirin have been crystallized from the melt in the presence of salicylic acid either generated from aspirin decomposition or added deliberately (2.6–35.9 mol %). Scanning electron microscopy, X-ray diffraction analysis, and optical polarimetry show that the spherulites are composed of helicoidal crystallites twisted along the <010> growth directions. Mueller matrix imaging reveals radial oscillations in not only linear birefringence, but also circular birefringence, whose origin is explained through slight (~1.3°) but systematic splaying of individual lamellae in the film. Strain associated with the replacement of aspirin molecules by salicylic acid molecules in the crystal structure is computed to be large enough to work as the driving force for the twisting of crystallites.

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