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Life-long physical activity involvement and the risk of Ischemic Stroke in Southern China

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Open access
Authors
Lee, Andy
Liang, Wenbin
Date
2010
Type
Journal Article

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Lee, A. and Liang, W. 2010. Life-long physical activity involvement and the risk of Ischemic Stroke in Southern China. Stroke. 2010: Article ID 415241.
Source Title
Stroke
DOI
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School
Epidemiology and Biostatistics
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This article is published under the Open Access publishing model and distributed under the terms of the Creative Commons License http://creativecommons.org/licenses/by/3.0/ Please refer to the licence to obtain terms for any further reuse or distribution of this work

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Abstract

A case-control study was conducted in southern China to investigate the relationship between life-long physical activity involvement and the risk of ischemic stroke. Information on life-long physical activity exposure and other lifestyle characteristics was obtained from 374 incident stroke patients and 464 hospital-based controls using a validated and reliable questionnaire. Logistic regression analyses were performed to assess the association between life-long physical activity involvement and the ischemic stroke risk. The control subjects reported more involvement in physical activity over the life course than the stroke patients (P < .0 0 1). The risk of ischemic stroke was inversely associated with life-long physical activity exposure, with adjusted odds ratio 0.39 (95% confidence interval 0.25 to 0.59) for participants who had always been involved relative to those who have never been much involved. The dose-response relationship was also significant (P < .0 0 1). Therefore, being active life long should be encouraged to prevent this major chronic disease.