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dc.contributor.authorHoogwout, S.
dc.contributor.authorPaananen, M.
dc.contributor.authorSmith, Anne
dc.contributor.authorBeales, Darren
dc.contributor.authorO'Sullivan, Peter
dc.contributor.authorStraker, Leon
dc.contributor.authorEastwood, P.
dc.contributor.authorMcArdle, N.
dc.contributor.authorChampion, D.
dc.date.accessioned2017-01-30T13:51:54Z
dc.date.available2017-01-30T13:51:54Z
dc.date.created2015-10-29T04:08:29Z
dc.date.issued2015
dc.identifier.citationHoogwout, S. and Paananen, M. and Smith, A. and Beales, D. and O'Sullivan, P. and Straker, L. and Eastwood, P. et al. 2015. Musculoskeletal pain is associated with restless legs syndrome in young adults. BMC Musculoskeletal Disorders. 16: 294.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/35822
dc.identifier.doi10.1186/s12891-015-0765-1
dc.description.abstract

Background - In recent years, there is considerable evidence of a relationship between the sensorimotor disorder restless legs syndrome (RLS) and pain disorders, including migraine and fibromyalgia. An association between multi-site pain and RLS has been reported in adult women. In the current study, we explored the association between musculoskeletal (MSK) pain and RLS in a large cohort of young adults. Methods - Twenty two year olds (n = 1072), followed since birth of part of the Western Australian Pregnancy Cohort (Raine) Study, provided data on MSK pain (duration, severity, frequency, number of pain sites). RLS was considered present when 4 diagnostic criteria recommended by the International Restless Legs Syndrome Study Group were met (urge to move, dysaesthesia, relief by movement, worsening symptoms during the evening/night) and participants had these symptoms at least 5 times per month. Associations between MSK pain and RLS were analyzed by multivariable logistic regression with bias-corrected bootstrapped confidence intervals, with final models adjusted for sex, psychological distress and sleep quality. Results - The prevalence of RLS was 3.0 % and MSK pain was reported by 37.4 % of the participants. In multivariable logistic regression models, strong associations were found between RLS-diagnosis and long duration (three months or more) of MSK pain (odds ratio 3.6, 95 % confidence interval 1.4–9.2) and reporting three or more pain sites (4.9, 1.6–14.6). Conclusions - Different dimensions of MSK pain were associated with RLS in young adults, suggestive of shared pathophysiological mechanisms. Overlap between these conditions requires more clinical and research attention.

dc.titleMusculoskeletal pain is associated with restless legs syndrome in young adults
dc.typeJournal Article
dcterms.source.volume16
dcterms.source.number1
dcterms.source.titleBMC Musculoskeletal Disorders
curtin.note

This open access article is distributed under the Creative Commons license http://creativecommons.org/licenses/by/4.0/

curtin.departmentSchool of Physiotherapy and Exercise Science
curtin.accessStatusOpen access


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