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    Publications from clinical trials: Process, conflict of interest and the evidence base

    Access Status
    Fulltext not available
    Authors
    Binns, Colin
    Low, W.
    Date
    2013
    Type
    Journal Article
    
    Metadata
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    Citation
    Binns, C. and Low, W. 2013. Publications from clinical trials: Process, conflict of interest and the evidence base. Preventive Medicine. 57 (SUPPL): pp. S3-S4.
    Source Title
    Preventive Medicine
    DOI
    10.1016/j.ypmed.2013.04.005
    ISSN
    0091-7435
    School
    School of Public Health
    Remarks

    From Special Issue: 1st Asia Pacific Clinical Epidemiology and Evidence Based Medicine Conference

    URI
    http://hdl.handle.net/20.500.11937/35983
    Collection
    • Curtin Research Publications
    Abstract

    Objectives: The aim of this study is to review the issues of publication of clinical trials with consideration of ethics and the incomplete evidence base. Methods:We review clinical trials and issues of communications and ethics. Several case studies of notable public health researchers will be discussed. Results:Many of the major breakthroughs of public health practice, including the works of John Snow would not have been published under modern guidelines for scientific communication. The research-publication system of modern health care poses many challenges for editors. Journal editors need to include a balance of different types of studies where insufficient randomised controlled trials are available. Conclusion:Clinical trials are a reliable source of evidence for health care practitioners. Journals need to uphold the integrity of the information provided by randomised controlled trials (RCTs) and synthesise and communicate health information. At the same time, editors must assess non-RCT evidence and be vigilant for many of the other potential problems in health and medical communication. © 2013 Elsevier Inc.

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