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    Safety of anti-rheumatic drugs for rheumatoid arthritis in pregnancy and lactation

    246015_246015.pdf (421.3Kb)
    Access Status
    Open access
    Authors
    Ngian, G.
    Briggs, Andrew
    Ackerman, I.
    Van Doornum, S.
    Date
    2016
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Ngian, G. and Briggs, A. and Ackerman, I. and Van Doornum, S. 2016. Safety of anti-rheumatic drugs for rheumatoid arthritis in pregnancy and lactation. International Journal of Rheumatic Diseases. 19 (9): pp. 834-843.
    Source Title
    International Journal of Rheumatic Diseases
    DOI
    10.1111/1756-185X.12860
    ISSN
    1756-1841
    School
    School of Physiotherapy and Exercise Science
    Remarks

    This is the peer reviewed version of the following article: Ngian, G. and Briggs, A. and Ackerman, I. and Van Doornum, S. 2016. Safety of anti-rheumatic drugs for rheumatoid arthritis in pregnancy and lactation. International Journal of Rheumatic Diseases. 19 (9): pp. 834-843, which has been published in final form at http://doi.org/10.1111/1756-185X.12860. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving at http://olabout.wiley.com/WileyCDA/Section/id-820227.html#terms.

    URI
    http://hdl.handle.net/20.500.11937/36249
    Collection
    • Curtin Research Publications
    Abstract

    Women with rheumatoid arthritis (RA) are often of childbearing age and therefore questions regarding reproductive health and the use of medications, including disease-modifying anti-rheumatic drugs (DMARDs) may arise during the clinical consultation. Each patient requires individual assessment in order to effectively manage the disease while minimizing any treatment-associated risks to the fetus. Although good-quality controlled trials are lacking, there is an increasing volume of evidence surrounding the use of immunosuppressive therapies in pregnancy and lactation. This review summarizes the currently available information which can be of benefit to clinicians guiding patients and their families through the risks and benefits of continuing RA therapy during pregnancy and lactation. Further studies and ongoing surveillance of drug safety in pregnancy are required to resolve the uncertainties that remain regarding synthetic and biologic DMARDs.

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