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dc.contributor.authorPereira, Gavin
dc.contributor.authorBell, M.
dc.contributor.authorBelanger, K.
dc.contributor.authorde Klerk, N.
dc.date.accessioned2017-01-30T14:02:51Z
dc.date.available2017-01-30T14:02:51Z
dc.date.created2015-10-29T04:08:48Z
dc.date.issued2014
dc.identifier.citationPereira, G. and Bell, M. and Belanger, K. and de Klerk, N. 2014. Fine particulate matter and risk of preterm birth and pre-labor rupture of membranes in Perth, Western Australia 1997-2007: A longitudinal study. Environment International. 73: pp. 143-149.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/37440
dc.identifier.doi10.1016/j.envint.2014.07.014
dc.description.abstract

Objective: A recent longitudinal study reported an association between fine particulate (PM2.5) exposure and preterm birth (PTB) in a US cohort. We applied the same design to an Australian cohort to investigate associations with PTB and pre-labor rupture of membranes (PROM). Methods: From 287,680 births, we selected 39,189 women who had singleton births at least twice in Western Australia in 1997-2007 (n. = 86,844 births). Analyses matched pregnancies to the same women with conditional logistic regression. Results: For PROM adjusted odds ratios (ORs) for a 1µg/m3 increase in PM2.5 in the first trimester, second trimester, third trimester, and whole pregnancy were 1.00 (95% confidence interval (CI): 0.97, 1.03), 1.03 (95% CI: 1.00, 1.06), 1.02 (95% CI: 1.00, 1.05), and 1.02 (95% CI: 0.99, 1.05) respectively. For PTB, corresponding ORs were 1.00 (95% CI: 0.96, 1.04), 1.00 (95% CI: 0.96, 1.04), 0.98 (95% CI: 0.94, 1.02), and 0.99 (95% CI: 0.95, 1.04) respectively. Conclusion: Risk of PROM was greater for pregnancies with elevated PM2.5 exposure in the second trimester than were other pregnancies to the same Australian women at lower exposure. There was insufficient evidence for an association with PTB, indicating that a longer time period might be needed to observe an association if a causal effect exists. © 2014 Elsevier Ltd.

dc.publisherElsevier Ltd
dc.titleFine particulate matter and risk of preterm birth and pre-labor rupture of membranes in Perth, Western Australia 1997-2007: A longitudinal study
dc.typeJournal Article
dcterms.source.volume73
dcterms.source.startPage143
dcterms.source.endPage149
dcterms.source.issn0160-4120
dcterms.source.titleEnvironment International
curtin.accessStatusFulltext not available


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