Large-scale synthesis of both symmetrical and unsymmetrical triacylglycerols containing docosahexaenoic acid
| dc.contributor.author | Andrews, P. | |
| dc.contributor.author | Fraser, B. | |
| dc.contributor.author | Junk, P. | |
| dc.contributor.author | Massi, Massimiliano | |
| dc.contributor.author | Perlmutter, P. | |
| dc.contributor.author | Thienthong, N. | |
| dc.contributor.author | Wijesundera, C. | |
| dc.date.accessioned | 2017-01-30T14:10:10Z | |
| dc.date.available | 2017-01-30T14:10:10Z | |
| dc.date.created | 2012-12-03T07:24:54Z | |
| dc.date.issued | 2008 | |
| dc.identifier.citation | Andrews, Philip C. and Fraser, Benjamin H. and Junk, Peter C. and Massi, Massimiliano and Perlmutter, Patrick and Thienthong, Neeranat and Wijesundera, Chakra. 2008. Large-scale synthesis of both symmetrical and unsymmetrical triacylglycerols containing docosahexaenoic acid. Tetrahedron 64 (39): pp. 9197-9202. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/37946 | |
| dc.identifier.doi | 10.1016/j.tet.2008.07.058 | |
| dc.description.abstract |
A large-scale (~ to 100 g) synthesis of symmetrical and unsymmetrical triacylglycerols containing docosahexaenoic acid (D) and two of either lauric (L), palmitic (P) or stearic acid (S) is described. Key improvements in purification of synthetic intermediates, in addition to a more efficient acetonide cleavage reaction affords the six TAGs (LaDLa, LaLaD, PDP, PPD, SDS, SSD) in yields of 80-90% and in regioisomeric purities greater than or equal to 90%. | |
| dc.publisher | Pergamon-Elsevier Science Ltd | |
| dc.subject | lipase | |
| dc.subject | omega-3 | |
| dc.subject | interesterification | |
| dc.subject | structured triacylglycerols | |
| dc.subject | omega-3-fatty-acids | |
| dc.subject | Polyunsaturated fatty-acids | |
| dc.subject | disease | |
| dc.subject | chemoenzymatic synthesis | |
| dc.subject | oil | |
| dc.subject | retina | |
| dc.title | Large-scale synthesis of both symmetrical and unsymmetrical triacylglycerols containing docosahexaenoic acid | |
| dc.type | Journal Article | |
| dcterms.source.volume | 64 | |
| dcterms.source.number | 39 | |
| dcterms.source.startPage | 9197 | |
| dcterms.source.endPage | 9202 | |
| dcterms.source.issn | 00404020 | |
| dcterms.source.title | Tetrahedron | |
| curtin.department | ||
| curtin.accessStatus | Fulltext not available |