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dc.contributor.authorReid, Alison
dc.contributor.authorHeyworth, J.
dc.contributor.authorDe Klerk, N.
dc.contributor.authorMusk, A.
dc.date.accessioned2017-01-30T14:10:19Z
dc.date.available2017-01-30T14:10:19Z
dc.date.created2016-09-12T08:36:28Z
dc.date.issued2009
dc.identifier.citationReid, A. and Heyworth, J. and De Klerk, N. and Musk, A. 2009. Asbestos exposure and gestational trophoblastic disease: A hypothesis. Cancer Epidemiology Biomarkers and Prevention. 18 (11): pp. 2895-2898.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/37961
dc.identifier.doi10.1158/1055-9965.EPI-09-0731
dc.description.abstract

Among 2,968 women and girls exposed to crocidolite (blue asbestos) at Wittenoom, three cases of choriocarcinoma and three cases of hydatidiform mole have been identified (crude incidence rate of 9.9 per 1000 women and 1.7 per 1000 deliveries for choriocarcinoma and hydatidiform mole, respectively). The women with choriocarcinoma were resident at Wittenoom at the time of disease development, whereas hydatidiform mole occurred much later in women who had first been exposed to asbestos as young girls. Four of the six cases were known to have lived with asbestos company workers who brought their dusty work-clothes home for washing. Asbestos fibers have been reported in the lung, the pleural and peritoneal mesothelium, and the human ovary. They have also been detected in placental digests of live and stillborn infants. This cluster of gestational trophoblastic diseases has some biological plausibility for asbestos causation. Taking an occupational and residential history and examining pathologic specimens for asbestos fibers or bodies may prove useful in patients with gestational trophoblastic disease. Copyright © 2009 American Association for Cancer Research.

dc.publisherAmerican Association for Cancer Research Inc
dc.titleAsbestos exposure and gestational trophoblastic disease: A hypothesis
dc.typeJournal Article
dcterms.source.volume18
dcterms.source.number11
dcterms.source.startPage2895
dcterms.source.endPage2898
dcterms.source.issn1055-9965
dcterms.source.titleCancer Epidemiology Biomarkers and Prevention
curtin.departmentEpidemiology and Biostatistics
curtin.accessStatusOpen access via publisher


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