Ovarian cancer risk is reduced by prolonged lactation: A case-control study in southern China
dc.contributor.author | Su, D. | |
dc.contributor.author | Pasalich, Maria | |
dc.contributor.author | Lee, Andy | |
dc.contributor.author | Binns, Colin | |
dc.date.accessioned | 2017-01-30T10:34:40Z | |
dc.date.available | 2017-01-30T10:34:40Z | |
dc.date.created | 2013-05-16T20:00:22Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Su, Dada and Pasalich, Maria and Lee, Andy H. and Binns, Colin W. 2013. Ovarian cancer risk is reduced by prolonged lactation: A case-control study in southern China. American Journal of Clinical Nutrition. 97 (2): pp. 354-359. | |
dc.identifier.uri | http://hdl.handle.net/20.500.11937/3846 | |
dc.identifier.doi | 10.3945/ajcn.112.044719 | |
dc.description.abstract |
Background: Ovarian cancer is an important neoplasm that is difficult to diagnose and treat; therefore, prevention is the preferable strategy. Growing evidence indicates a protective effect of breastfeeding on ovarian cancer risk. Objective: The objective was to investigate the association between lactation and the risk of ovarian cancer among southern Chinese women. Design: A case-control study was undertaken in Guangzhou, Guangdong Province, between August 2006 and July 2008. A validated and reliable questionnaire was used to obtain information on the months of lactation and number of children breastfed in a sample of 493 incident ovarian cancer patients and 472 hospital-based controls (mean age: 59 y). Logistic regression analyses were performed to assess the association between breastfeeding and the risk of ovarian cancer. Results: Significant inverse dose-response relations were found for both duration of lactation and the number of children breastfed. The adjusted ORs were 0.09 (95% CI: 0.04, 0.19) for women with ≥31 mo of total lactation and those with ≤10 mo of lactation and 0.38 (95% CI: 0.27, 0.55) for women with ≥3 children breastfed compared with those with one child breastfed. Conclusion: Prolonged lactation is associated with a lower risk of ovarian cancer in parous Chinese women. | |
dc.publisher | American Society for Nutrition | |
dc.title | Ovarian cancer risk is reduced by prolonged lactation: A case-control study in southern China | |
dc.type | Journal Article | |
dcterms.source.volume | 97 | |
dcterms.source.startPage | 354 | |
dcterms.source.endPage | 359 | |
dcterms.source.issn | 0002-9165 | |
dcterms.source.title | American Journal of Clinical Nutrition | |
curtin.department | ||
curtin.accessStatus | Open access via publisher |