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    Asthma history predicts the risk of affective disorders and anxiety disorders

    193643_98330_Health_2013.pdf (111.3Kb)
    Access Status
    Open access
    Authors
    Liang, Wenbin
    Chikritzhs, Tanya
    Date
    2013
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Liang, Wenbin and Chikritzhs, Tanya. 2013. Asthma history predicts the risk of affective disorders and anxiety disorders. Health. 5 (2A): pp. 313-319.
    Source Title
    Health
    DOI
    10.4236/health.2013.52A042
    ISSN
    19494998
    Remarks

    This article is published under the Open Access publishing model and distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/. Please refer to the licence to obtain terms for any further reuse or distribution of this work.

    URI
    http://hdl.handle.net/20.500.11937/39125
    Collection
    • Curtin Research Publications
    Abstract

    Background: Positive associations between asthma and a range of mental disorders have been increasingly reported in cross-sectional studies. It is important to determine whether the association between asthma and mental disorders may be causal. Objectives: We conducted a retrospective cohort study using data collected from the 2007 Australia Mental Health and Wellbeing survey (MHW) to examine whether preexisting asthma may predict the likelihood of various types of anxiety disorders and affective disorders. Design, Settings and Subjects: The 2007 MHW survey was a nationally representative household survey. Its data included 8841 Australian adults aged 18 - 85 yrs. Age at first onset of asthma and mental disorders were used to reveal the order of occurrence of asthma and mental disorders, and to define time at risk and asthma exposure. Kaplan-Meier failure function and multivariate Poisson regression models were employed in analysis. Results: Participants who had a history of asthma that lasted six months or more were at higher risk of panic disorder, obsessive compulsive disorder, posttraumatic stress disorder, bipolar disorder, mania and hypomania. The association between asthma history and risk of mental disorder subtypes differed by gender. Conclusion: The findings of this study support the hypothesis that pre-existing asthma increases the risk of a number of anxiety disorders and affective disorders. Predisposition to carbon dioxide hypersensitivity and corticosteroid therapy may partly explain the observed associations.

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