A randomized controlled trial of a decision aid for women considering genetic testing for breast and ovarian cancer risk
MetadataShow full item record
PURPOSE: To measure the effectiveness of a tailored decision aid (DA) designed to help women make informed decisions about genetic testing for breast/ovarian cancer risk. METHODS: A total of 145 women were randomized to receive the DA or a control pamphlet at the end of their first genetic counseling consultation. Of these, 120 (82.8%) completed two questionnaires, 1 week and 6 months post-consultation. RESULTS: While the DA had no effect on informed choice, post-decisional regret or actual genetic testing decision, the trial showed that women who received the DA had higher knowledge levels and felt more informed about genetic testing than women who received the control pamphlet (chi(2)(2) = 6.82; P = 0.033; chi(2)(1) = 4.86; P = 0.028 respectively). The DA also helped women who did not have blood drawn at their first consultation to clarify their values with regards to genetic testing (chi(2)(1) = 5.27; P = 0.022). Women who received the DA were less likely to share the information with other family members than women in the control condition (chi(2)(1) = 8.78; P = 0.003). CONCLUSIONS: Decision aids are an effective decision-support strategy for women considering genetic testing for breast/ovarian cancer risk, and are most effective before the patient has made a decision, which is generally at the point of having blood drawn.
The original publication is available at: http://www.springerlink.com
Showing items related by title, author, creator and subject.
Quality of life in women during and after treatment for breast cancer: a systematic review of qualitative evidenceDevi, M.; Hegney, Desley (2011)Background: Breast cancer is the most common cancer in women. With increasing numbers of women surviving breast cancer, there is a need to move beyond the traditional ways of evaluating clinical outcomes and include ...
Investigating barriers to genetic counseling and germline mutation testing in women with suspected hereditary breast and ovarian cancer syndrome and Lynch syndromeShaw, J.; Bulsara, C.; Cohen, P.; Gryta, M.; Nichols, C.; Schofield, L.; O'Sullivan, S.; Pachter, N.; Hardcastle, Sarah (2018)© 2017 Elsevier B.V. Objective: The aim of the current study was to explore barriers to genetic counseling and testing in women with gynecological cancers deemed at significant risk of carrying a germline mutation. Methods: ...
Treatment-focused DNA testing for newly diagnosed breast cancer patients: some implications for clinical practiceLobb, Elizabeth; Barlow-Stewart, K.; Suthers, G.; Hallowell, N. (2010)There is accumulating evidence that women with breast cancer due to a familial BRCA1 or BRCA2 mutation benefit from specific surgical and chemotherapeutic treatment strategies. However, the rapid identification of such ...