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Plaque Formation at the Left Coronary Artery: Analysis of the Relationship Between Arterial Angulations and Hemodynamics

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Open access
Authors
Chachaina, T.
Sun, Zhonghua
Wong, K.
Tu, J.
Date
2010
Type
Conference Paper

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Citation
Chachaina, Thanapong and Sun, Zhonghua and Wong, K.L. and Tu, Jiyuan. 2010. Plaque Formation at the Left Coronary Artery: Analysis of the Relationship Between Arterial Angulations and Hemodynamics, in Assawinchaichote, W. (ed), The 30th IASTED Conference on Modelling, Identification, and Control - AsiaMIC 2010, Nov 24 2010, pp. 1-6. Phuket, Thailand: ACTA Press.
Source Title
International Association of Science and Technology for Development
Source Conference
The 30th IASTED Conference on Modelling, Identification, and Control - AsiaMIC 2010
School
Department of Imaging and Applied Physics
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Collection
Abstract

We investigate the relationship between coronary angulations and their hemodynamic effect. Six left coronary models were generated based on the anatomical details of patient specific data. Varying angles at 90°, 75°, 60°, 45°, 30° and 15° between the left anterior descending and the left circumflex branches are simulated. Numerical simulation is used to analyse flow velocity, wall pressure and wall shear stress under normal physiological conditions of human body in different cardiac cycles. Our results showed that the wall shear stress was significantly decreased in models of higher angulations. In contrast, high wall pressure occurred at coronary bifurcation regions with those models. Our preliminary study demonstrates that there is direct relationship between angulations at the left coronary artery and development of atherosclerosis.