Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial
MetadataShow full item record
Background: Regular consumption of diets with increased protein or fibre intakes may benefit body weight and composition and cardiovascular disease risk factors. Lupin flour is a novel food ingredient high in protein and fibre.Objective: To investigate the effects of a lupin-enriched diet, during and following energy restriction, on body weight and composition and cardiovascular disease risk factors in overweight individuals.Design: Participants (n=131) were recruited to a 12-month parallel-design trial. They were randomly assigned to consume lupin-enriched foods or matching high-carbohydrate control foods. All participants underwent 3 months of weight loss, 1 month of weight stabilization and 8 months of weight maintenance. Body weight and composition and cardiovascular disease risk factors were assessed at baseline, 4 and 12 months.Results: Lupin, relative to control, did not significantly influence (mean difference (95% CI)) weight loss at 4 months (0.1?kg (-1.2, 1.4)) and 12 months (-0.6?kg (-2.0, 0.8)), maintenance of weight loss from 4 to 12 months (-0.7?kg (-1.83, 0.48)) or measures of body fat and fat-free mass. Relative to control, 24-h ambulatory systolic (-1.3?mm?Hg (-2.4, -0.3), P=0.016) and diastolic (-1.0?mm?Hg (-1.9, -0.2), P=0.021) blood pressures were lower at 12 months but not at 4 months; fasting insulin concentrations and homeostasis model assessment (HOMA) scores were significantly lower at 4 months (-1.2?mU?l–1 (-1.3, -1.1), P=0.004 and -0.6 units (-1.0, -0.19), P=0.004) and 12 months (-1.3 mU?l–1 (-1.4, -1.1), P<0.001 and -0.7 units (-1.1, -0.24), P=0.002).Conclusions: A diet higher in protein and fibre derived from lupin-enriched foods does not enhance weight loss or improve the maintenance of weight loss. However, such a diet may provide cardiovascular health benefits in terms of insulin sensitivity and blood pressure.
Showing items related by title, author, creator and subject.
Inoue, Madoka (2012)This thesis examines infant feeding practices, including knowledge and attitudes towards breastfeeding, factors that influence the duration of breastfeeding, and breastfeeding outcomes in relation to postpartum women’s ...
Living well after breast cancer randomized controlled trial protocol: evaluating a telephone-delivered weight loss intervention versus usual care in women following treatment for breast cancerReeves, M.; Terranova, C.; Erickson, J.; Job, J.; Brookes, D.; McCarthy, N.; Hickman, I.; Lawler, S.; Fjeldsoe, B.; Healy, Genevieve; Winkler, E.; Janda, M.; Veerman, J.; Ware, R.; Prins, J.; Vos, T.; Demark-Wahnefried, W.; Eakin, E. (2016)BACKGROUND: Obesity, physical inactivity and poor diet quality have been associated with increased risk of breast cancer-specific and all-cause mortality as well as treatment-related side-effects in breast cancer survivors. ...
Improving Nutrition and Activity Behaviors Using Digital Technology and Tailored Feedback: Protocol for the LiveLighter Tailored Diet and Activity (ToDAy) Randomized Controlled TrialHalse, Rhiannon E; Shoneye, Charlene L; Pollard, Christina; Jancey, Jonine; Scott, Jane; Pratt, Iain S; Dhaliwal, Satvinder S; Norman, Richard; Straker, Leon M; Boushey, C.; Delp, E.; Zhu, F.; Harray, Amelia J; Szybiak, Maria A; Finch, Anne; McVeigh, J.; Mullan, Barbara; Collins, C.; Mukhtar, Syed Aqif; Edwards, Kieran N; Healy, Janelle D; Kerr, Deborah (2019)Background: Excess weight is a major risk factor for chronic diseases. In Australia, over 60% of adults are overweight or obese. The overconsumption of energy-dense nutrient-poor (EDNP) foods and low physical activity ...