Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls
MetadataShow full item record
Evidence that fructose intake may modify blood pressure is generally limited to adult populations. This study examined cross-sectional associations between dietary intake of fructose, serum uric acid and blood pressure in 814 adolescents aged 13–15 years participating in the Western Australian Pregnancy Cohort (Raine) Study. Energy-adjusted fructose intake was derived from 3-day food records, serum uric acid concentration was assessed using fasting blood and resting blood pressure was determined using repeated oscillometric readings. In multivariate linear regression models, we did not see a significant association between fructose and blood pressure in boys or girls. In boys, fructose intake was independently associated with serum uric acid (P<0.01), and serum uric acid was independently associated with systolic blood pressure (P<0.01) and mean arterial pressure (P<0.001). Although there are independent associations, there is no direct relationship between fructose intake and blood pressure. Our data suggest that gender may influence these relationships in adolescence, with significant associations observed more frequently in boys than girls.
The following article appeared in Bobridge, Kelly and Haines, Gemma and Mori, Trevor and Beilin, Lawrie and Oddy, Wendy and Sherriff, Jillian and O'Sullivan, Therese. 2013. Dietary fructose in relation to blood pressure and serum uric acid in adolescent boys and girls. Journal of Human Hypertension 27 (4): pp. 217-224 and may be found at http://www.nature.com/jhh/journal/v27/n4/full/jhh201236a.html.
Showing items related by title, author, creator and subject.
GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican AmericansChittoor, G.; Kent, J.; Almeida, M.; Puppala, S.; Farook, V.; Cole, S.; Haack, K.; Göring, H.; MacCluer, J.; Curran, J.; Carless, M.; Johnson, M.; Moses, Eric; Almasy, L.; Mahaney, M.; Lehman, D.; Duggirala, R.; Comuzzie, A.; Blangero, J.; Voruganti, V. (2016)Background: The variation in serum uric acid concentrations is under significant genetic influence. Elevated SUA concentrations have been linked to increased risk for gout, kidney stones, chronic kidney disease, and ...
Probucol prevents blood–brain barrier dysfunction and cognitive decline in mice maintained on pro-diabetic dietMamo, John; Lam, Virginie; Brook, E.; Mooranian, A.; Al-Salami, Hani; Fimognari, N.; Nesbit, M.; Takechi, Ryu (2018)© The Author(s) 2018. An emerging body of evidence consistently suggests that compromised blood–brain barrier integrity may be causally associated with cognitive decline induced by type-2 diabetes. Our previous studies ...
Woolley, S.; Sherriff, Jill; Oddy, W.; O'Sullivan, T. (2013)Aim: This research aimed to cross-sectionally quantify fructose consumption and identify major food sources of fructose in adolescents participating in the 14-year follow up of the Western Australian Pregnancy Cohort ...