Using an electrical potential to reversibly switch surfaces between two states for dynamically controlling cell adhesion
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Authors
Ng, C.
Magenau, A.
Ngalim, S.
Ciampi, Simone
Chockalingham, M.
Harper, J.
Gaus, K.
Gooding, J.
Date
2012Type
Journal Article
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Ng, C. and Magenau, A. and Ngalim, S. and Ciampi, S. and Chockalingham, M. and Harper, J. and Gaus, K. et al. 2012. Using an electrical potential to reversibly switch surfaces between two states for dynamically controlling cell adhesion. Angewandte Chemie - International Edition. 51 (31): pp. 7706-7710.
Source Title
Angewandte Chemie - International Edition
ISSN
School
Nanochemistry Research Institute
Collection
Abstract
Smart surfaces presenting both antifouling molecules with a charged functional group at their distal end, and molecules that are terminated by RGD peptides for cell adhesion, were fabricated and characterized (see picture). By applying potentials of +300 or −300 mV, the surfaces could be dynamically switched to make the peptide accessible or inaccessible to cells.