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    Using an electrical potential to reversibly switch surfaces between two states for dynamically controlling cell adhesion

    Access Status
    Fulltext not available
    Authors
    Ng, C.
    Magenau, A.
    Ngalim, S.
    Ciampi, Simone
    Chockalingham, M.
    Harper, J.
    Gaus, K.
    Gooding, J.
    Date
    2012
    Type
    Journal Article
    
    Metadata
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    Citation
    Ng, C. and Magenau, A. and Ngalim, S. and Ciampi, S. and Chockalingham, M. and Harper, J. and Gaus, K. et al. 2012. Using an electrical potential to reversibly switch surfaces between two states for dynamically controlling cell adhesion. Angewandte Chemie - International Edition. 51 (31): pp. 7706-7710.
    Source Title
    Angewandte Chemie - International Edition
    DOI
    10.1002/anie.201202118
    ISSN
    1433-7851
    School
    Nanochemistry Research Institute
    URI
    http://hdl.handle.net/20.500.11937/41798
    Collection
    • Curtin Research Publications
    Abstract

    Smart surfaces presenting both antifouling molecules with a charged functional group at their distal end, and molecules that are terminated by RGD peptides for cell adhesion, were fabricated and characterized (see picture). By applying potentials of +300 or −300 mV, the surfaces could be dynamically switched to make the peptide accessible or inaccessible to cells.

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