Surgical Management in Patients With Pancreatic Cancer: a Queensland Perspective
MetadataShow full item record
Background: Little has been published regarding presenting symptoms, investigations and outcomes for patients with pancreatic cancer in Australia. Data from a series of patients undergoing attempted resection in Queensland, Australia, are presented with the aim of assisting development of consistent strategies in disease management.Methods: We reviewed the medical records of 121 patients who underwent attempted surgical resection and who took part in a case-control study between 2007 and 2009. Information relating to symptoms, investigations, surgical procedures and outcomes was captured.Results: The mean age was 63 years and 60% were men. The most common presenting symptoms were jaundice (64%) and pain (63%). Over 80% of patients had multiple imaging investigations or laparoscopy prior to surgery. Seventy-eight patients (64%) had a completed resection and 23% of these had involved margins. The presence of metastases and/or involvement of vessels or adjacent structures precluded resection in the remaining patients. The 1-year survival for patients whose resections were completed was 77% compared with 51% for those whose tumours were notresectable (P = 0.004). There was no 30-day mortality and 68% of patients were alive 1 year after diagnosis. Resections were performed in 11 different hospitals but over 90% of patients underwent their surgery in one of five high-volume centres.Conclusion: The Queensland experience is consistent with that reported internationally. A significant proportion of attempted resections was not completed because preoperative staging underestimated disease extent. Most patients with potentially resectable disease are being treated in high-volume centres.
Showing items related by title, author, creator and subject.
Wylie, N.; Adib, R.; Barbour, A.; Fawcett, J.; Hill, A.; Lynch, S.; Martin, I.; O'Rourke, T.; Puhalla, H.; Rutherford, L.; Slater, K.; Whiteman, D.; Neale, R.; Fritschi, Lin (2013)Background: Little has been published regarding presenting symptoms, investigations and outcomes for patients with pancreatic cancer in Australia. Data from a series of patients undergoing attempted resection in Queensland, ...
Physiotherapy practice patterns for patients undergoing surgery for lung cancer: a survey of hospitals in Australia and New ZealandCavalheri de Oliveira, Vinicius; Jenkins, Susan; Hill, Kylie (2013)Background: There has been a recent increase in the research available to guide physiotherapy management of patients who require surgical resection for lung cancer. It is unclear whether this evidence has influenced ...
Platell, Cameron; Spilsbury, Katrina (2014)Background: Recent trials on rectal cancer have demonstrated significant improvements in local recurrence without improvements in overall survival. The aim of this paper was to define the influence of local recurrence on ...