Structure-activity relationship of karrikin germination stimulants

Flematti, G.; Scaffidi, A.; Goddard-Borger, E.; Heath, C.; Nelson, D.; Commander, L.; Stick, R.; Dixon, Kingsley; Smith, S.; Ghisalberti, E.

doi:10.1021/jf101690a

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Authors

Flematti, G.

Scaffidi, A.

Goddard-Borger, E.

Heath, C.

Nelson, D.

Commander, L.

Stick, R.

Dixon, Kingsley

Smith, S.

Ghisalberti, E.

Date

2010

Type

Journal Article

Metadata

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Citation

Flematti, G. and Scaffidi, A. and Goddard-Borger, E. and Heath, C. and Nelson, D. and Commander, L. and Stick, R. et al. 2010. Structure-activity relationship of karrikin germination stimulants. Journal of Agriculture and Food Chemistry. 58 (15): pp. 8612-8617.

Source Title

Journal of Agriculture and Food Chemistry

DOI

10.1021/jf101690a

ISSN

0021-8561

School

Department of Environment and Agriculture

URI

http://hdl.handle.net/20.500.11937/43926

Collection

Curtin Research Publications

Abstract

Karrikins (2H-furo[2,3-c]pyran-2-ones) are potent smoke-derived germination promoters for a diverse range of plant species but, to date, their mode of action remains unknown. This paper reports the structure-activity relationship of numerous karrikin analogues to increase understanding of the key structural features of the molecule that are required for biological activity. The results demonstrate that modification at the C5 position is preferred over modification at the C3, C4, or C7 positions for retaining the highest bioactivity. © 2010 American Chemical Society.