Antifungal properties of nanosized ZnS particles synthesised by sonochemical precipitation
MetadataShow full item record
Zinc sulphide (ZnS) nanoparticles, synthesised by a sonochemical route employing zinc chloride and sodium sulphide, displayed significant antifungal properties against the pathogenic yeast Candida albicans (MTCC 227) at a minimum fungicidal concentration of 300 µg ml<sup>-1</sup>. The antifungal properties of zinc sulphide particles is attributed to the generation of reactive oxygen species due to the interaction of the nanoparticles with water. Additionally, the presence of Zn in the zone of inhibition and the absence of antifungal effects for large micron sized particles of ZnS suggest a size induced effect leading to perturbation of fungal cell membranes, resulting in growth inhibition. © The Royal Society of Chemistry.
Showing items related by title, author, creator and subject.
Thangavelu Rajan, Remya (2008)Objective: To retrospectively evaluate intravenous antifungal medications in paediatric patients in a public hospital for children.Method: Data relevant to the antifungal prescription were collected for all the patients ...
Viegelmann, C.; Margassery, L.; Kennedy, J.; Zhang, T.; O'Brien, C.; O'Gara, Fergal; Morrissey, J.; Dobson, A.; Edrada-Ebel, R. (2014)Metabolomics and genomics are two complementary platforms for analyzing an organism as they provide information on the phenotype and genotype, respectively. These two techniques were applied in the dereplication and ...
Malayamycin, a new streptomycete antifungal compound, specifically inhibits sporulation of Stagonospora nodorum, cause of wheat glume blotch diseaseLi, W.; Csukai, M.; Corran, A.; Crowley, P.; Solomon, P.; Oliver, Richard (2008)BACKGROUND: Malayamycin is a novel perhydrofuropyran C-nucleoside isolated from Streptomyces malaysiensis that shows promising antifungal activity, fully controlling a range of diseases when applied to plants at 100 µg ...