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    Antifungal properties of nanosized ZnS particles synthesised by sonochemical precipitation

    Access Status
    Fulltext not available
    Authors
    Suyana, P.
    Kumar, S.
    Kumar, B.
    Nair, Balagopal
    Pillai, S.
    Mohamed, A.
    Warrier, K.
    Hareesh, U.
    Date
    2014
    Type
    Journal Article
    
    Metadata
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    Citation
    Suyana, P. and Kumar, S. and Kumar, B. and Nair, B. and Pillai, S. and Mohamed, A. and Warrier, K. et al. 2014. Antifungal properties of nanosized ZnS particles synthesised by sonochemical precipitation. RSC Advances. 4 (17): pp. 8439-8445.
    Source Title
    RSC Advances
    DOI
    10.1039/c3ra46642f
    School
    Nanochemistry Research Institute
    URI
    http://hdl.handle.net/20.500.11937/44599
    Collection
    • Curtin Research Publications
    Abstract

    Zinc sulphide (ZnS) nanoparticles, synthesised by a sonochemical route employing zinc chloride and sodium sulphide, displayed significant antifungal properties against the pathogenic yeast Candida albicans (MTCC 227) at a minimum fungicidal concentration of 300 µg ml<sup>-1</sup>. The antifungal properties of zinc sulphide particles is attributed to the generation of reactive oxygen species due to the interaction of the nanoparticles with water. Additionally, the presence of Zn in the zone of inhibition and the absence of antifungal effects for large micron sized particles of ZnS suggest a size induced effect leading to perturbation of fungal cell membranes, resulting in growth inhibition. © The Royal Society of Chemistry.

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