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dc.contributor.authorChapman, H.
dc.contributor.authorEramudugolla, R.
dc.contributor.authorGavrilescu, M.
dc.contributor.authorStrudwick, M.
dc.contributor.authorLoftus, Andrea
dc.contributor.authorCunnington, R.
dc.contributor.authorMattingley, J.
dc.date.accessioned2017-01-30T15:24:01Z
dc.date.available2017-01-30T15:24:01Z
dc.date.created2015-03-03T03:50:55Z
dc.date.issued2010
dc.identifier.citationChapman, H. and Eramudugolla, R. and Gavrilescu, M. and Strudwick, M. and Loftus, A. and Cunnington, R. and Mattingley, J. 2010. Neural mechanisms underlying spatial realignment during adaptation to optical wedge prisms. Neuropsychologia. 48: pp. 2595-2601.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/45900
dc.identifier.doi10.1016/j.neuropsychologia.2010.05.006
dc.description.abstract

Visuomotor adaptation to a shift in visual input produced by prismatic lenses is an example of dynamicsensory-motor plasticity within the brain. Prism adaptation is readily induced in healthy individuals, andis thought to reflect the brain’s ability to compensate for drifts in spatial calibration between differentsensory systems. The neural correlate of this form of functional plasticity is largely unknown, althoughcurrent models predict the involvement of parieto-cerebellar circuits. Recent studies that have employedevent-related functional magnetic resonance imaging (fMRI) to identify brain regions associated withprism adaptation have discovered patterns of parietal and cerebellar modulation as participants corrected their visuomotor errors during the early part of adaptation. However, the role of these regions inthe later stage of adaptation, when ‘spatial realignment’ or true adaptation is predicted to occur, remainsunclear. Here, we used fMRI to quantify the distinctive patterns of parieto-cerebellar activity as visuomotor adaptation develops. We directly contrasted activation patterns during the initial error correction phase of visuomotor adaptation with that during the later spatial realignment phase, and found significant recruitment of the parieto-cerebellar network – with activations in the right inferior parietal lobe and the right posterior cerebellum. These findings provide the first evidence of both cerebellar and parietal involvement during the spatial realignment phase of prism adaptation.

dc.publisherPergamon
dc.subjectSpatial realignment
dc.subjectPrism adaptation
dc.subjectCerebellum
dc.subjectSpatial cognition
dc.subjectError correction
dc.subjectfMRI
dc.subjectParietal lobe
dc.titleNeural mechanisms underlying spatial realignment during adaptation to optical wedge prisms
dc.typeJournal Article
dcterms.source.volume48
dcterms.source.startPage2595
dcterms.source.endPage2601
dcterms.source.issn00283932
dcterms.source.titleNeuropsychologia
curtin.accessStatusFulltext not available


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