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    Long-term effects of a protein-enriched diet on blood pressure in older women

    172056_47437_Long-term effects of a protein-enriched.pdf (102.3Kb)
    Access Status
    Open access
    Authors
    Hodgson, J.
    Zhu, K.
    Lewis, J.
    Kerr, Deborah
    Meng, Xingqiong
    Solah, Vicky
    Devine, A.
    Binns, Colin
    Woodman, J.
    Prince, R.
    Date
    2012
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Hodgson, Jonathan M. and Zhu, Kun and Lewis, Joshua R. and Kerr, Deborah and Meng, Xingqiong and Solah, Vicky and Devine, Amanda and Binns, Colin W. and Woodman, Richard J. and Prince, Richard L. 2012. Long-term effects of a protein-enriched diet on blood pressure in older women. British Journal of Nutrition. 107 (11): pp. 1664-1672.
    Source Title
    British Journal of Nutrition
    DOI
    10.1017/S0007114511004740
    ISSN
    00071145
    School
    Nutrition, Dietetics, Food Science & Environmental Health
    Remarks

    Copyright © 2011 The Authors

    URI
    http://hdl.handle.net/20.500.11937/46230
    Collection
    • Curtin Research Publications
    Abstract

    Short-term randomised, controlled trials have found that dietary protein relative to carbohydrate can reduce blood pressure. Our objective was to investigate the effects on blood pressure of an increase in protein intake from whey over 2 years in women aged over 70 years. From the general population, 219 women aged between 70 and 80 years were recruited to a 2-year randomised, double-blind, placebo-controlled parallel-design trial: 181 women completed the trial to the end of year 2. Participants were randomly assigned to consume a daily whey protein-based beverage (protein) or an energy-matched low-protein high-carbohydrate beverage (control). Blood pressure measurements were performed at baseline, year 1 and year 2. For protein relative to control, the estimated mean net differences in protein and carbohydrate intakes were 18 (95 % CI 13, 23) and − 22 (95 % CI − 9, − 35) g/d at year 1, and 22 (95 % CI 17, 28) and − 18 (95 % CI − 6, − 31) g/d at year 2. Intention-to-treat analysis found no overall differences between groups in blood pressure (P>0.5). Net differences in systolic and diastolic blood pressure were – 2.3 (95 % CI – 5.3, 0.7) and – 1.5 (95 % CI – 3.6, 0.6) mmHg at year 1, and 1.6 (95 % CI – 1.5, 4.7) and 0.3 (95 % CI – 1.9, 2.4) mmHg at year 2. Similar differences in systolic and diastolic blood pressure at years 1 and 2 were observed with per-protocol analysis. Therefore, the present study did not provide evidence that a higher whey protein intake in older women can have prolonged effects on blood pressure.

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