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    Impact of Surface Nano-textured Stainless Steel Prepared by Focused Ion Beam on Endothelial Cell Growth

    Access Status
    Fulltext not available
    Authors
    Nazneen, F.
    Schmidt, M.
    McLoughlin, E.
    Petkov, N.
    Herzog, G.
    Arrigan, Damien
    Galvin, P.
    Date
    2013
    Type
    Journal Article
    
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    Citation
    Nazneen, Feroze and Schmidt, Michael and McLoughlin, Eve and Petkov, Nikolay and Herzog, Gregoire and Arrigan, Damien W.M. and Galvin, Paul. 2013. Impact of Surface Nano-textured Stainless Steel Prepared by Focused Ion Beam on Endothelial Cell Growth. Journal of Nanoscience and Nanotechnology. 13 (8): pp. 5283-5290.
    Source Title
    Journal of Nanoscience and Nanotechnology
    DOI
    10.1166/jnn.2013.7476
    ISSN
    15334880
    URI
    http://hdl.handle.net/20.500.11937/47130
    Collection
    • Curtin Research Publications
    Abstract

    The modification of stent surfaces with nano-structures has the potential for limiting late stent restenosis. We report here the patterning of 316L austentitic stainless steel with arrays of nano-pits of two nominal diameters: 120 and 180 nm. These nano-textured surfaces were prepared by focused ion beam milling. The influence of the ion beam current on the nano-features was investigated by scanning electron and atomic force microscopies. The optimum ion beam currents were 280 pA for 120 nm nano-pits and 920 pA for 180 nm nano-pits. The depths of the nano-pits formed were (65±24) nm (120 nm) and (84±36) nm (180 nm). This wide distribution of the depths is due to the polycrystalline nature of 316 L stainless steel, which has a strong influence on the milling rates. Endothelial cells were grown in vitro on these substrates for 1, 3 and 5 days. The cells were viable for the duration of the cell culture on the nano-textured substrates. There was no significant difference in the adhesion and the proliferation based on the nano-pit diameter.

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