Secondary amine catalyzed retro-aldol reactions of enals and enones: one-pot conversion of enals to [alpha]-substituted derivatives
| dc.contributor.author | Enders, D. | |
| dc.contributor.author | Nguyen, Thanh Vinh | |
| dc.date.accessioned | 2017-01-30T10:41:26Z | |
| dc.date.available | 2017-01-30T10:41:26Z | |
| dc.date.created | 2014-11-19T01:13:25Z | |
| dc.date.issued | 2012 | |
| dc.identifier.citation | Enders, D. and Nguyen, T.V. 2012. Secondary amine catalyzed retro-aldol reactions of enals and enones: one-pot conversion of enals to [alpha]-substituted derivatives. Tetrahedron Letters. 53 (16): pp. 2091-2095. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/4742 | |
| dc.description.abstract |
A practical synthetic procedure to hydrolytically cleave the C,C-double bond of a,b-unsaturated aldehydes and ketones has been developed. Secondary amines are employed as organocatalysts for the retro-aldol process under simple and mild reaction conditions. Beside the generation of the parent aromatic aldehydes, the synthetic procedure has been successfully used in a one-pot reaction sequence to convert simple cinnamaldehydes into their a-aryl/alkyl substituted derivatives. | |
| dc.publisher | Pergamon | |
| dc.relation.uri | http://www.sciencedirect.com/science/article/pii/S0040403912002663 | |
| dc.subject | Retro-aldol | |
| dc.subject | Iminium activation | |
| dc.subject | b-Unsaturated aldehydes | |
| dc.subject | a | |
| dc.subject | Organocatalysis | |
| dc.subject | Cinnamaldehyde | |
| dc.title | Secondary amine catalyzed retro-aldol reactions of enals and enones: one-pot conversion of enals to [alpha]-substituted derivatives | |
| dc.type | Journal Article | |
| dcterms.source.volume | 53 | |
| dcterms.source.number | 16 | |
| dcterms.source.startPage | 2091 | |
| dcterms.source.endPage | 2095 | |
| dcterms.source.issn | 0040-4039 | |
| dcterms.source.title | Tetrahedron Letters | |
| curtin.accessStatus | Fulltext not available |