Anesthesia, Sleep, and Upper Airway Collapsibility
MetadataShow full item record
Anesthesia and sleep both predispose to upper airway obstruction through state-induced reductions in pharyngeal dilator muscle activation and lung volume. The tendencies are related in patients with obstructive sleep apnea commonly presenting with difficulties in airway management in the perioperative period. This is a period of great potential vulnerability for such patients because of compromise of the arousal responses that protect against asphyxiation during natural sleep. Careful preoperative evaluation and insightful perioperative observation are likely to identify patients at risk. A significant proportion of patients will have previously undiagnosed obstructive sleep apnea and anesthesiologists are well placed to identify this potential. Patients with known or suspected obstructive sleep apnea need careful postoperative management, particularly while consciousness and arousal responses are impaired. Specific follow-up of suspected cases is needed to ensure that the sleep-related component of the problem receives appropriate care. © 2010 Elsevier Inc.
Showing items related by title, author, creator and subject.
Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activitySpina, G.; Spruit, M.; Alison, J.; Benzo, R.; Calverley, P.; Clarenbach, C.; Costello, R.; Donaire-Gonzalez, D.; Dürr, S.; Garcia-Aymerich, J.; van Gestel, A.; Gramm, M.; Hernandes, N.; Hill, Kylie; Hopkinson, N.; Jarreta, D.; Kohler, M.; Kirsten, A.; Leuppi, J.; Magnussen, H.; Maltais, F.; Man, W.; McKeough, Z.; Mesquita, R.; Miedinger, D.; Pitta, F.; Singh, S.; Smeenk, F.; Tal-Singer, R.; Vagaggini, B.; Waschki, B.; Watz, H.; Wouters, E.; Zogg, S.; den Brinker, A. (2017)Background: Sleep disturbances are common in patients with chronic obstructive pulmonary disease (COPD) with a considerable negative impact on their quality of life. However, factors associated with measures of sleep in ...
Shepherd, K.; Hillman, D.; Holloway, R.; Eastwood, Peter (2011)Purpose: Obstructive sleep apnea (OSA) is associated with increased nocturnal gastroesophageal reflux (nocturnal GER) events and symptoms. Treatment of OSA with continuous positive airway pressure (CPAP) reduces nocturnal ...
Acute upper airway responses to hypoglossal nerve stimulation during sleep in obstructive sleep apneaSchwartz, A.; Barnes, M.; Hillman, D.; Malhotra, A.; Kezirian, E.; Smith, P.; Hoegh, T.; Parrish, D.; Eastwood, Peter (2012)Rationale: Hypoglossal nerve stimulation (HGNS) recruits lingual muscles, reduces pharyngeal collapsibility, and treats sleep apnea. Objectives: We hypothesized that graded increases in HGNS relieve pharyngeal obstruction ...