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dc.contributor.authorSpahn, D.
dc.contributor.authorTheusinger, O.
dc.contributor.authorHofmann, Axel
dc.date.accessioned2017-03-15T22:06:27Z
dc.date.available2017-03-15T22:06:27Z
dc.date.created2017-02-24T00:09:07Z
dc.date.issued2012
dc.identifier.citationSpahn, D. and Theusinger, O. and Hofmann, A. 2012. Patient blood management is a win-win: a wake -up call. British Journal of Anaesthesia. 108 (6): pp. 889-892.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/49645
dc.description.abstract

Preoperative anaemia is frequent in surgical patients and increases postoperative mortality, major morbidity, and length of hospital stay. Poorly controlled bleeding and surgical blood loss can also contribute to these outcomes. Anaemia, blood loss, and liberal transfusion triggers are the main predictors for red blood cell (RBC) transfusion. RBC transfusion in turn is an additional independent predictor for adverse outcome and has therefore been referred to as the ‘second hit’ for the recipient. Transfusion outcomes include higher mortality, more ischaemic complications, organ dysfunction, infections, delayed wound healing, and increased length of hospital stay. Transfused patients may also be more likely to develop non-Hodgkin lymphoma. Interestingly, most of these complications are found after administration of just a single RBC unit.1011 Strict application of the Bradford-Hill criteria strongly suggests that the link between transfusion and adverse outcomes is causal and not just associative.

dc.publisherOxford University Press
dc.subjectblood loss
dc.subjectanaemia
dc.subjectmortality
dc.subjecttransfusion
dc.subjectmorbidity
dc.subjectpatient blood management
dc.titlePatient blood management is a win-win: a wake -up call
dc.typeJournal Article
dcterms.source.volume108
dcterms.source.number6
dcterms.source.startPage889
dcterms.source.endPage892
dcterms.source.issn0007-0912
dcterms.source.titleBritish Journal of Anaesthesia
curtin.departmentCentre for Population Health Research
curtin.accessStatusFulltext not available


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