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    The effects of pulmonary rehabilitation in patients with non-cystic fibrosis bronchiectasis: protocol for a randomised controlled trial

    215848_40615_58541_publishedversion.pdf (739.5Kb)
    Access Status
    Open access
    Authors
    Lee, A.
    Cecins, Nola
    Hill, C.
    Holland, A.
    Rautela, L.
    Stirling, R.
    Thompson, P.
    McDonald, C.
    Jenkins, Susan
    Date
    2010
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Lee, A. and Cecins, N. and Hill, C. and Holland, A. and Rautela, L. and Stirling, R. and Thompson, P. et al. 2010. The effects of pulmonary rehabilitation in patients with non-cystic fibrosis bronchiectasis: protocol for a randomised controlled trial. BMC Pulmonary Medicine. 10 (5).
    Source Title
    BMC Pulmonary Medicine
    DOI
    10.1186/1471-2466-10-5
    ISSN
    1471-2466
    School
    School of Physiotherapy and Exercise Science
    Remarks

    This article is published under the Open Access publishing model and distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/2.0/. Please refer to the licence to obtain terms for any further reuse or distribution of this work.

    URI
    http://hdl.handle.net/20.500.11937/4999
    Collection
    • Curtin Research Publications
    Abstract

    Background: Non-cystic fibrosis bronchiectasis is characterised by sputum production, exercise limitation and recurrent infections. Although pulmonary rehabilitation is advocated for this patient group, its effects are unclear. The aims of this study are to determine the short and long term effects of pulmonary rehabilitation on exercise capacity, cough, quality of life and the incidence of acute pulmonary exacerbations. Methods/Design: This randomised controlled trial aims to recruit 64 patients with bronchiectasis from three tertiary institutions. Participants will be randomly allocated to the intervention group (supervised, twice weekly exercise training with regular review of airway clearance therapy) or a control group (twice weekly telephone support). Measurements will be taken at baseline, immediately following the intervention and at six and 12 months following the intervention period by a blinded assessor. Exercise capacity will be measured using the incremental shuttle walk test and the six-minute walk test. Quality of life and health status will be measured using the Chronic Respiratory Questionnaire, Leicester Cough Questionnaire, Assessment of Quality of Life Questionnaire and the Hospital Anxiety and Depression Scale. The rate of hospitalisation will be captured as well as the incidence of acute pulmonary exacerbations using a daily symptom diary. Discussion: Results from this study will help to determine the efficacy of supervised twice-weekly pulmonary rehabilitation upon exercise capacity and quality of life in patients with bronchiectasis and will contribute to clinical practice guidelines for physiotherapists in the management of this population.

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