Curtin University Homepage
  • Library
  • Help
    • Admin

    espace - Curtin’s institutional repository

    JavaScript is disabled for your browser. Some features of this site may not work without it.
    View Item 
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item
    • espace Home
    • espace
    • Curtin Research Publications
    • View Item

    Challenges in the health economics of familial hypercholesterolemia

    Access Status
    Fulltext not available
    Authors
    Norman, Richard
    Watts, G.
    Weintraub, W.
    Gidding, S.
    Date
    2016
    Type
    Journal Article
    
    Metadata
    Show full item record
    Citation
    Norman, R. and Watts, G. and Weintraub, W. and Gidding, S. 2016. Challenges in the health economics of familial hypercholesterolemia. Current Opinion in Lipidology. 27 (6): pp. 563-569.
    Source Title
    Current Opinion in Lipidology
    DOI
    10.1097/MOL.0000000000000365
    ISSN
    0957-9672
    School
    Department of Health Policy and Management
    URI
    http://hdl.handle.net/20.500.11937/50406
    Collection
    • Curtin Research Publications
    Abstract

    Purpose of review: Implementation of effective interventions often requires evidence regarding value, that is, whether they are worth what we pay for them. This review explores recent evidence concerning cost-effectiveness in familial hypercholesterolemia, and discusses the cause of, and likelihood of solutions to, the paucity of such evidence. Recent findings: Cost-effectiveness analysis in familial hypercholesterolemia has been limited almost exclusively to adult populations. However, there is growing evidence that childhood intervention offers substantial benefit in terms of downstream health gains. Statin therapy in adults has been demonstrated to be cost-effective, but the range of novel agents that might be used will require de novo economic evaluation alongside exploration of their effect and safety profile. Summary: The familial hypercholesterolemia field has limited evidence regarding cost-effectiveness, which limits optimum allocation of resources. Economic evaluations are necessary to appraise new agents and optimal timing of management approaches. Evaluations often have substantial data demands; consequentially, their applicability to medical decision-making or policy will be partly determined by the availability of data, particularly those providing information about the long-term trajectory of health benefit from familial hypercholesterolemia treatment. Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved.

    Related items

    Showing items related by title, author, creator and subject.

    • Cascade screening based on genetic testing is cost-effective: Evidence for the implementation of models of care for familial hypercholesterolemia
      Ademi, Z.; Watts, G.; Pang, J.; Sijbrands, E.; Van Bockxmeer, F.; O'Leary, Peter; Geelhoed, E.; Liew, D. (2014)
      Background: Familial hypercholesterolemia (FH) imposes significant burden of premature coronary heart disease (CHD). Objective: This study aimed to determine the cost-effectiveness of FH detection based on genetic testing, ...
    • Cost-effectiveness of a cascade screening program for the early detection of familial hypercholesterolemia
      Lázaro, P.; Pérez de Isla, L.; Watts, G.; Alonso, R.; Norman, Richard; Muñiz, O.; Fuentes, F.; Mata, N.; López-Miranda, J.; González-Juanatey, J.; Díaz-Díaz, J.; Blasco, A.; Mata, P. (2016)
      Background: Although familial hypercholesterolemia (FH) confers a high risk of coronary artery disease, most patients are undiagnosed, and little is known about the efficiency of genetic cascade screening programs at ...
    • Health literacy in familial hypercholesterolemia: A cross-national study
      Hagger, Martin; Hardcastle, Sarah; Hu, M.; Kwok, S.; Lin, J.; Nawawi, H.; Pang, J.; Santos, R.; Soran, H.; Su, T.; Tomlinson, B.; Watts, G. (2018)
      Background: High rates of inadequate health literacy are associated with maladaptive health outcomes in chronic disease including increased mortality and morbidity rates, poor treatment adherence and poor health. Adequate ...
    Advanced search

    Browse

    Communities & CollectionsIssue DateAuthorTitleSubjectDocument TypeThis CollectionIssue DateAuthorTitleSubjectDocument Type

    My Account

    Admin

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Follow Curtin

    • 
    • 
    • 
    • 
    • 

    CRICOS Provider Code: 00301JABN: 99 143 842 569TEQSA: PRV12158

    Copyright | Disclaimer | Privacy statement | Accessibility

    Curtin would like to pay respect to the Aboriginal and Torres Strait Islander members of our community by acknowledging the traditional owners of the land on which the Perth campus is located, the Whadjuk people of the Nyungar Nation; and on our Kalgoorlie campus, the Wongutha people of the North-Eastern Goldfields.