Baseline investigations of folate status in Aboriginal and non-Aboriginal West Australians prior to the introduction of mandatory fortification
MetadataShow full item record
Objective: In September 2009, Australia implemented mandatory folic acid fortification of wheat flour for bread-making to reduce the incidence of neural tube defects. Our study aimed to establish baseline folate status data in Aboriginal and non-Aboriginal Western Australians. Methods: Patients who presented at a health service or collection centre for blood tests were invited to participate. One hundred and ninety-one Aboriginals and 159 non-Aboriginals were recruited between April 2008 and September 2009. Participants completed a five-minute questionnaire and had blood taken for red blood cell (RBC) folate and serum vitamin B12. Data were analysed using SPSS (version 17.0.2, SPSS Inc., Chicago, IL, USA).Results: Ten per cent (95% confidence intervals (CI): 5, 19) of the Aboriginal women participants and 26% (95% CI:16, 40) of men had RBC folate concentrations below 250 ng/mL, the cut-off associated with folate deficiency. None of the non-Aboriginal women (95% CI: 0, 4) and 4% of the non-Aboriginal men (95% CI: 2, 12) had RBC folate concentrations below 250 ng/mL. All participants were vitamin B12 replete. None of the 96 Aboriginal and 8% of non- Aboriginal women aged 16–44 reported consumption of supplements with a daily intake of >400 µg folic acid during the previous week. Conclusions and implications: This study established a baseline of RBC folate, folate consumption and supplement use in Aboriginal and non-Aboriginal groups. We identified 10% of Aboriginal women and none of non-Aboriginal women participants with low folate concentrations. The higher prevalence of folate deficiency in Aboriginal participants suggests they are more likely to benefit from a universal program of folate fortification.
Showing items related by title, author, creator and subject.
Folate status in Aboriginal people before and after mandatory fortification of flour for bread-making in AustraliaBower, C.; Maxwell, S.; Hickling, S.; D'Antoine, H.; O'Leary, Peter (2015)Background: Mandatory fortification of wheat flour for bread-making was introduced in Australia in September 2009, to assist in the prevention of neural tube defects (NTD). NTD are twice as common in Aboriginal compared ...
Towards understanding disparities in cancer outcomes for Aboriginal Australians: exploring Aboriginal perceptions and experiences of cancer in Western AustraliaShahid, Shaouli (2010)Cancer has become one of the major chronic diseases among Aboriginal and Torres Strait Islander people of Australia, and was declared a health priority in the National Aboriginal and Torres Strait Islander Health Strategy ...
Complex impact of remoteness on the incidence of myocardial infarction in Aboriginal and non-Aboriginal people in Western AustraliaKatzenellenbogen, Judith; Sanfilippo, Frank; Hobbs, Michael; Briffa, Tom; Knuiman, Matthew; Dimer, Lyn; Thompson, Peter; Thompson, Sandra (2012)Objective: To determine the impact of remoteness on Aboriginal and non-Aboriginal myocardial infarction incidence rates in men and women of different ages. Design: Descriptive study. Setting: Western Australia. Participants: ...