Risk factors for malignant mesothelioma in people with no known exposure to asbestos
MetadataShow full item record
Objectives: Malignant mesothelioma (MM) is a rare and generally fatal cancer, usually caused by asbestos, although about 5-10% of cases report no asbestos exposure. This study aimed to identify sources whereby people in Western Australia (WA) may be unknowingly exposed to asbestos or to other exposures which may cause MM. Methods: Cases with no known asbestos exposure were selected from the WA Mesothelioma Register (WAMR). Matched controls were selected from hospital patients admitted for conditions unrelated to asbestos. Occupational histories were coded by an industrial hygienist. Data were analyzed using conditional logistic regression. Results: Thirty-eight MM participants and 134 controls were recruited. Risk of MM was increased (OR=3.1, 95%CI 1.0-9.6) after no known, but likely, exposure to asbestos at work. Conclusions: Because of its extensive use, few people in WA have never been exposed to asbestos. Unrecognized exposure may cause most MM cases initially regarded as "no exposure."
Showing items related by title, author, creator and subject.
Development of a job-exposure matrix (AsbJEM) to estimate occupational exposure to asbestos in AustraliaVan Oyen, S.; Peters, S.; Alfonso, Helman; Fritschi, L.; De Klerk, N.; Reid, Alison; Franklin, P.; Gordon, L.; Benke, G.; Musk, A. (2015)Introduction: Occupational exposure data on asbestos are limited and poorly integrated in Australia so that estimates of disease risk and attribution of disease causation are usually calculated from data that are not ...
Franklin, P.; Alfonso, H.; Reid, A.; Olsen, N.; Shilkin, K.; Brims, Fraser; de Klerk, N.; Musk, A. (2016)Background: Malignant mesothelioma (MM) has distinct histological subtypes (epithelioid, sarcomatoid and biphasic) with variable behaviour and prognoses. It is well recognised that survival time varies with the histological ...
Increasing incidence of malignant mesothelioma after exposure to asbestos during home maintenance and renovationOlsen, N.; Franklin, P.; Reid, Alison; de Klerk, N.; Threlfall, T.; Shilkin, K.; Musk, B. (2011)Objective: To determine trends in incidence of malignant mesothelioma (MM) caused by exposure to asbestos during home maintenance and renovation. Design, setting and participants: Using the Western Australian Mesothelioma ...