Live Metabolite-Deficient Bordetella pertussis: Determination of Suitability for use as a Vaccine in Humans using the Pertussis Mouse Model
MetadataShow full item record
This thesis embodies research that has demonstrated that there is strong case for further development of novel live attenuated metabolite deficient B pertussis vaccine such that it is non-toxic because it polarises the immune response of DTaP-vaccinated mice from Th2 to Th1 following booster vaccination with the live attenuated vaccine thus offering the chance of long term protection against whooping cough and disrupting the transmission from adolescents and adults to infants.
Showing items related by title, author, creator and subject.
Modelling the co-occurence of Streptococcus pneumoniae with other bacterial and viral pathogens in the upper respiratory tractJacoby, P.; Watson, K.; Bowman, J.; Taylor, A.; Riley, T.; Smith, D.; Lehmann, Deborah (2007)Go to ScienceDirect® Home Skip Main Navigation Links Brought to you by: The University of Western Australia Library Login: + Register Athens/Institution Login Not Registered? - User Name: Password: ...
The impact of pandemic A(H1N1)pdm09 influenza and vaccine-associated adverse events on parental attitudes and influenza vaccine uptake in young childrenBlyth, C.; Richmond, P.; Jacoby, P.; Thornton, P.; Regan, Annette; Robins, C.; Kelly, H.; Smith, D.; Effler, P. (2014)Introduction: Parental attitudes towards vaccination significantly influence vaccine uptake. The A(H1N1)pdm09 influenza pandemic was followed in 2010 by an unprecedented increase in febrile reactions in children receiving ...
Enkel, S.; Attwell, K.; Snelling, Thomas; Christian, H. (2017)Objective: Some parents are hesitant about vaccines and yet still vaccinate their children. Vaccine behaviours are not fixed and parents who are concerned but nonetheless adherent to standard schedules could switch to an ...