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dc.contributor.authorAlhashmi, Ibrahim
dc.contributor.supervisorAssoc. Prof. Trilochan Mukkuren_US
dc.contributor.supervisorProf. John Wetherallen_US

This thesis embodies research that has demonstrated that there is strong case for further development of novel live attenuated metabolite deficient B pertussis vaccine such that it is non-toxic because it polarises the immune response of DTaP-vaccinated mice from Th2 to Th1 following booster vaccination with the live attenuated vaccine thus offering the chance of long term protection against whooping cough and disrupting the transmission from adolescents and adults to infants.

dc.publisherCurtin Universityen_US
dc.titleLive Metabolite-Deficient Bordetella pertussis: Determination of Suitability for use as a Vaccine in Humans using the Pertussis Mouse Modelen_US
curtin.departmentSchool of Biomedical Sciencesen_US
curtin.accessStatusOpen accessen_US
curtin.facultyHealth Sciencesen_US

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