Simple synthesis of 2-amino-4-(het)aryl-4,6-dihydro-1(3)(11)H-[1,3,5]triazino[2,1-b]quinazolin-6-ones

Dolzhenko, Anton; Dolzhenko, A.; Chui, W.

doi:10.1002/jhet.5570450119

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Authors

Dolzhenko, Anton

Dolzhenko, A.

Chui, W.

Date

2008

Type

Journal Article

Metadata

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Citation

Dolzhenko, Anton V. and Dolzhenko, Anna V. and Chui, Wai-Keung. 2008. Simple synthesis of 2-amino-4-(het)aryl-4,6-dihydro-1(3)(11)H-[1,3,5]triazino[2,1-b]quinazolin-6-ones. Journal of Heterocyclic Chemistry. 45 (1): pp. 173-176.

Source Title

Journal of Heterocyclic Chemistry

DOI

10.1002/jhet.5570450119

ISSN

0022-152X

School

School of Pharmacy

URI

http://hdl.handle.net/20.500.11937/5210

Collection

Curtin Research Publications

Abstract

The 2-amino-4-(het)aryl-4,6-dihydro-1(3)(11)H-[1,3,5]triazino[2,1-b]quinazolin-6-ones were prepared readily by cyclocondensation of anthranilic acid derived 4-oxo-3,4-dihydroquinazolinyl-2-guanidine with a variety of aldehydes. The structures of the compounds were confirmed by nmr spectroscopy, including 2D NOESY experiments.