Liver-mediated shedding of platelet GPVI
| dc.contributor.author | Berndt, Michael | |
| dc.contributor.author | Andrews, R. | |
| dc.date.accessioned | 2017-06-23T02:59:29Z | |
| dc.date.available | 2017-06-23T02:59:29Z | |
| dc.date.created | 2017-06-19T03:39:28Z | |
| dc.date.issued | 2016 | |
| dc.identifier.citation | Berndt, M. and Andrews, R. 2016. Liver-mediated shedding of platelet GPVI. Blood. 128 (6): pp. 751-752. | |
| dc.identifier.uri | http://hdl.handle.net/20.500.11937/53319 | |
| dc.identifier.doi | 10.1182/blood-2016-07-723973 | |
| dc.description.abstract |
The in vivo mechanisms underlying antibody-based shedding of the key platelet collagen receptor glycoprotein VI (GPVI) are potentially significant for future antibody-based thromboprotective agents. In this issue of Blood, Stegner et al reveal how the inhibitory Fc receptor, Fc g RIIB, on mouse liver sinusoidal endothelium mediates both antibody-induced GPVI shedding and entrapment of platelets in the liver. | |
| dc.publisher | American Society of Hematology | |
| dc.title | Liver-mediated shedding of platelet GPVI | |
| dc.type | Journal Article | |
| dcterms.source.volume | 128 | |
| dcterms.source.number | 6 | |
| dcterms.source.startPage | 751 | |
| dcterms.source.endPage | 752 | |
| dcterms.source.issn | 0006-4971 | |
| dcterms.source.title | Blood | |
| curtin.accessStatus | Open access via publisher | |
| curtin.faculty | Faculty of Health Sciences |
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