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    A Cluster RCT to Reduce Workers’ Sitting Time: Impact on Cardiometabolic Biomarkers

    Access Status
    Fulltext not available
    Authors
    Healy, Genevieve
    Winkler, E.
    Eakin, E.
    Owen, N.
    LaMontagne, A.
    Moodie, M.
    Dunstan, D.
    Date
    2017
    Type
    Journal Article
    
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    Citation
    Healy, G. and Winkler, E. and Eakin, E. and Owen, N. and LaMontagne, A. and Moodie, M. and Dunstan, D. 2017. A Cluster RCT to Reduce Workers’ Sitting Time: Impact on Cardiometabolic Biomarkers. Medicine and Science in Sports and Exercise. 49 (10): pp. 2032–2039.
    Source Title
    Medicine and Science in Sports and Exercise
    DOI
    10.1249/MSS.0000000000001328
    ISSN
    0195-9131
    School
    School of Physiotherapy and Exercise Science
    URI
    http://hdl.handle.net/20.500.11937/53391
    Collection
    • Curtin Research Publications
    Abstract

    Purpose: To evaluate the initial and long-term impacts on cardio-metabolic health indicators of the Stand Up Victoria intervention — a 12-month, multicomponent workplace-delivered intervention that successfully reduced overall sitting time, primarily by increasing standing time. Methods: Office worksites (≥1km apart) from a single organization were cluster randomized to intervention (n=7) or control (n=7). Participants were 136 intervention and 95 control desk-based workers (5–39 per worksite; 68% women; mean±SD age = 45.6±9.4 years). Outcomes, assessed at baseline (0 months), three months, and 12 months, were 14 individual biomarkers of body composition, blood pressure, glucose metabolism, lipid metabolism and a composite overall cardio-metabolic risk score. Intervention effects were assessed by linear mixed models, accounting for repeated measures and clustering, baseline values and potential confounders. Missing data were multiply imputed. Significance was set at p<0.05, two-tailed. Results: No significant intervention effects were observed at three months. Significant effects, favoring intervention, were observed at 12 months for fasting glucose (-0.34, 95%CI -0.65, -0.03, p=0.028 mmol/L) and the overall cardio-metabolic risk score (-0.16, 95%CI -0.30, -0.03, p=0.019). Other intervention effects were typically weakly in favor of the intervention group, but were non-significant and estimated with wide confidence intervals. Conclusions: In “healthy” workers (not selected as having any specific health condition), a workplace intervention showed a small benefit for improving biomarkers of cardio-metabolic risk, but only with 12 months of intervention and not for all biomarkers. Long term facilitation of movement and standing at work may be a useful approach to reducing cardiovascular disease risk in the working population. The potential benefits for workers at high risk for cardiovascular disease (e.g., with diabetes) may be even greater and merit investigation.

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    • Reducing office workers' sitting time: Rationale and study design for the Stand Up Victoria cluster randomized trial
      Dunstan, D.; Wiesner, G.; Eakin, E.; Neuhaus, M.; Owen, N.; Lamontagne, A.; Moodie, M.; Winkler, E.; Fjeldsoe, B.; Lawler, S.; Healy, Genevieve (2013)
      Background: Excessive time spent in sedentary behaviours (sitting or lying with low energy expenditure) is associated with an increased risk for type 2 diabetes, cardiovascular disease and some cancers. Desk-based office ...
    • Cardiometabolic Impact of Changing Sitting, Standing, and Stepping in the Workplace
      Winkler, E.; Chastin, S.; Eakin, E.; Owen, N.; Lamontagne, A.; Moodie, M.; Dempsey, P.; Kingwell, B.; Dunstan, D.; Healy, Genevieve (2018)
      Background: According to cross-sectional and acute experimental evidence, reducing sitting time should improve cardiometabolic health risk biomarkers. Furthermore, the improvements obtained may depend on whether sitting ...
    • Replacing sitting time with standing or stepping: associations with cardio-metabolic risk biomarkers
      Healy, Genevieve; Winkler, E.; Owen, N.; Anuradha, S.; Dunstan, D. (2015)
      Aims: While excessive sitting time is related adversely to cardio-metabolic health, it is unknown whether standing is a suitable replacement activity or whether ambulatory movement is required. Using isotemporal substitution ...
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