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dc.contributor.authorShen, Y.
dc.contributor.authorZhong, Y.
dc.contributor.authorWang, H.
dc.contributor.authorMa, L.
dc.contributor.authorWang, Y.
dc.contributor.authorPan, J.
dc.contributor.authorZhang, K.
dc.contributor.authorSun, Zhonghua
dc.contributor.authorYe, H.
dc.identifier.citationShen, Y. and Zhong, Y. and Wang, H. and Ma, L. and Wang, Y. and Pan, J. and Zhang, K. et al. 2017. MR imaging features of benign retroperitoneal extra-adrenal paragangliomas. Scientific Reports. 7 (4517): pp. 1-9.

The goal of this study was to retrospectively review the magnetic resonance imaging (MRI) features of retroperitoneal extra-adrenal paragangliomas and to evaluate the diagnostic capabilities of MRI. Twenty-four patients with confirmed benign retroperitoneal extra-adrenal paragangliomas who underwent preoperative MRI and surgical resection were enrolled. The patients’ clinical characteristics and MRI features were reviewed by two radiologists. There were no significant differences in the qualitative and quantitative MRI features were determined by the reviewers. High signal intensity in T2- weighted imaging (T2WI) and diffusion-weighted imaging (DWI) was observed in all tumors. In contrast T1-weighted imaging (T1WI) in the arterial phase, 83.33% of the tumors were clearly enhanced. In 87.5% of cases, a persistent enhancement pattern was observed in the venous and delayed phases, and 12.5% of tumors showed a “washout” pattern. The tumor capsule, intratumoral septum and degenerations were visualized in the tumors and may be helpful in the qualitative diagnosis of extraadrenal paragangliomas in MRI. MRI was useful in locating the position, determining the tumor ranges and visualizing the relationship between the tumors and adjacent structures. The presence of typical clinical symptoms and positivity of biochemical tests are also important factors in making an accurate preoperative diagnosis.

dc.publisherNature Publishing Group
dc.titleMR imaging features of benign retroperitoneal extra-adrenal paragangliomas
dc.typeJournal Article
dcterms.source.titleScientific Reports
curtin.departmentDepartment of Medical Radiation Sciences
curtin.accessStatusOpen access

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