The effects of active mobilisation and rehabilitation in ICU on mortality and function: a systematic review.
MetadataShow full item record
Purpose: Early active mobilisation and rehabilitation in the intensive care unit (ICU) is being used to prevent the long-term functional consequences of critical illness. This review aimed to determine the effect of active mobilisation and rehabilitation in the ICU on mortality, function, mobility, muscle strength, quality of life, days alive and out of hospital to 180 days, ICU and hospital lengths of stay, duration of mechanical ventilation and discharge destination, linking outcomes with the World Health Organization International Classification of Function Framework. Methods: A PRISMA checklist-guided systematic review and meta-analysis of randomised and controlled clinical trials. Results: Fourteen studies of varying quality including a total of 1753 patients were reviewed. Active mobilisation and rehabilitation had no impact on short- or long-term mortality (p > 0.05). Meta-analysis showed that active mobilisation and rehabilitation led to greater muscle strength (body function) at ICU discharge as measured using the Medical Research Council Sum Score (mean difference 8.62 points, 95% confidence interval (CI) 1.39–15.86), greater probability of walking without assistance (activity limitation) at hospital discharge (odds ratio 2.13, 95% CI 1.19–3.83), and more days alive and out of hospital to day 180 (participation restriction) (mean difference 9.69, 95% CI 1.7–17.66). There were no consistent effects on function, quality of life, ICU or hospital length of stay, duration of mechanical ventilation or discharge destination. Conclusion: Active mobilisation and rehabilitation in the ICU has no impact on short- and long-term mortality, but may improve mobility status, muscle strength and days alive and out of hospital to 180 days.
Showing items related by title, author, creator and subject.
Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trialSchaller, S.; Anstey, Matthew; Blobner, M.; Edrich, T.; Grabitz, S.; Gradwohl-Matis, I.; Heim, M.; Houle, T.; Kurth, T.; Latronico, N.; Lee, J.; Meyer, M.; Peponis, T.; Talmor, D.; Velmahos, G.; Waak, K.; Walz, J.; Zafonte, R.; Eikermann, M. (2016)© 2016 Elsevier LtdBackground Immobilisation predicts adverse outcomes in patients in the surgical intensive care unit (SICU). Attempts to mobilise critically ill patients early after surgery are frequently restricted, ...
Evaluating the effects of increasing physical activity to optimize rehabilitation outcomes in hospitalized older adults (MOVE Trial): Study protocol for a randomized controlled trialSaid, C.; Morris, M.; McGinley, J.; Szoeke, C.; Workman, B.; Liew, D.; Hill, Keith; Woodward, M.; Wittwer, J.; Churilov, L.; Ventura, C.; Bernhardt, J. (2015)Background: Older adults who have received inpatient rehabilitation often have significant mobility disability at discharge. Physical activity levels in rehabilitation are also low. It is hypothesized that providing ...
Exploring different models of stroke unit care and outcome : the Stroke Rehabilitation Outcome (SRO) studyDennis, Diane (2013)Introduction: Stroke is a significant cardiovascular event requiring sub-acute rehabilitation, best provided in a stroke unit (SU). These units include dedicated neurological SUs usually catering only for patients with ...