Barriers to receiving hepatitis c treatment for people who inject drugs myths and evidence
MetadataShow full item record
Background: Alcohol consumption, current injecting drug use, and pre-existing mental illness have been identified as 3 of the main reasons for excluding patients from treatment for hepatitis C. Objectives: We reviewed the literature to obtain an evidence base for these common exclusion criteria. Materials and Methods: We reviewed original research and meta-analyses investigating the effects of alcohol consumption, current injecting drug use, and pre-existing mental illness. Results: We identified 66 study reports relevant to the review, but found only limited evidence to support withholding of treatment on the basis of the 3 previously mentioned exclusion criteria. Conclusions: Currently, there is a lack of evidence for many of the barriers faced by patients in availing treatment for hepatitis C. Adherence to treatment routine was found to be a better predictor of sustained virological response than injecting drug or alcohol consumption during treatment period or the presence of a pre-existing mental disorder. Although several challenges remain, we need to ensure that treatment decisions are based on the best available evidence and the treatment is performed appropriately on a case-by-case basis. © 2011 Kowsar M.P.Co. All rights reserved.
Showing items related by title, author, creator and subject.
Loxley, Wendy; Hawks, D. (1994)This research was carried out in 1990 to examine high-risk injecting and sexual behaviour in a sample of injecting drug users (IDUs) in Perth. The study was a cross-sectional survey with a convenience sample drawn from ...
Lenton, Simon (2003)Purpose of the review: The present review addresses recent literature on the effectiveness of reducing drug-related harm in a number of domains which might be promoted, facilitated, hindered, or prohibited by drug policy. ...
Salmon, A.; Dwyer, Robyn; Jauncey, M.; van Beek, I.; Topp, L.; Maher, L. (2009)Background: The process of drug injection may give rise to vascular and soft tissue injuries and infections. The social and physical environments in which drugs are injected play a significant role in these and other ...