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dc.contributor.authorRamsey, K.
dc.contributor.authorMcGirr, C.
dc.contributor.authorStick, S.
dc.contributor.authorHall, Graham
dc.contributor.authorSimpson, S.
dc.date.accessioned2017-07-27T05:22:27Z
dc.date.available2017-07-27T05:22:27Z
dc.date.created2017-07-26T11:11:12Z
dc.date.issued2016
dc.identifier.citationRamsey, K. and McGirr, C. and Stick, S. and Hall, G. and Simpson, S. 2016. Effect of posture on lung ventilation distribution and associations with structure in children with cystic fibrosis. Journal of Cystic Fibrosis. 16 (6), pp. 713-718.
dc.identifier.urihttp://hdl.handle.net/20.500.11937/54872
dc.identifier.doi10.1016/j.jcf.2017.01.013
dc.description.abstract

Background: We assessed the effect of posture on ventilation distribution and the impact on associations with structural lung disease. Methods: Multiple breath washout (MBW) was performed in seated and supine postures in 25 healthy children and 21 children with CF. Children with CF also underwent a chest CT scan. Functional residual capacity (FRC), lung clearance index (LCI) and moment ratios were calculated from the MBW test. CT scans were evaluated for CF-related structural lung disease. Results: FRC was lower in the supine than in the seated posture, whereas LCI was higher in the supine than in the seated posture. In children with CF, associations between LCI and the extent of structural lung disease were stronger when performed in the supine posture. Conclusions: Body posture influences lung volumes and ventilation distribution in both healthy children and children with CF. MBW testing in the supine posture strengthened associations with structural lung damage.

dc.publisherElsevier
dc.titleEffect of posture on lung ventilation distribution and associations with structure in children with cystic fibrosis
dc.typeJournal Article
dcterms.source.issn1569-1993
dcterms.source.titleJournal of Cystic Fibrosis
curtin.departmentSchool of Physiotherapy and Exercise Science
curtin.accessStatusFulltext not available


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